We have other current jobs related to this field that you can find below
-
Columbus, Ohio, United States MERCK Full timeJob Description Role and Responsibilities: We are seeking an experienced talented scientist to join the Quantitative Pharmacology and Pharmacometrics - Immune/Oncology (QP2-IO) team in the role of Associate Director QP2-IO team is part of the Global Clinical Development organization and has oversight over drug development aspects related to clinical...
-
Senior Principal Engineer
2 weeks ago
Columbus, Ohio, United States JPMorganChase Full timeJob Description We're looking for a technology leader ready to take their career to new heights. Join the ranks of top talent at one of the world's most influential companies.As a Senior Principal Software Engineer at JPMorgan Chase within the Legal & Regulatory Control Operations product, you provide deep engineering expertise and work across agile teams to...
-
Senior Research Scientist
4 days ago
Columbus, Ohio, United States UpStart Full timeAbout UpstartUpstart is a premier AI lending platform collaborating with financial institutions to enhance access to affordable credit. By utilizing Upstart's AI-driven marketplace, our partner banks and credit unions can achieve improved approval rates and reduced loss rates across diverse demographics, while providing an outstanding digital-first lending...
-
Principal Research Scientist
4 days ago
Columbus, Ohio, United States UpStart Full timeAbout UpstartUpstart is a prominent AI-driven lending platform collaborating with financial institutions to enhance access to affordable credit. By utilizing Upstart's AI marketplace, our partner banks and credit unions can achieve improved approval rates and reduced loss rates across diverse demographics, while providing an exceptional digital-first lending...
-
Senior Civil Engineering Leader
4 days ago
Columbus, Ohio, United States Insight Global Full timePosition: Senior Civil Engineering LeaderLocation: Ohio (Flexible options available)Compensation: $130,000 - $170,000 Role Overview:Insight Global is in search of a Senior Civil Engineering Leader to enhance our expanding engineering division in Ohio. The successful candidate will engage in a variety of engineering initiatives and contribute to our...
-
Senior Team Leader for Credit Review
4 days ago
Columbus, Ohio, United States Huntington Bancshares, Inc. Full timeSenior Team Leader for Credit ReviewThe Senior Team Leader for Credit Review will oversee a dedicated team engaged in assessing credit risk and conducting ongoing monitoring tasks. This position reports to the Credit Review Group Manager and demands exceptional leadership capabilities along with substantial experience in credit evaluation and project...
-
Quality Control Scientist II
2 weeks ago
Columbus, Ohio, United States Actalent Full timeJob Title: Quality Control Scientist II Job Description The individual will work primarily in the Quality Department to support the testing and analysis of cGMP produced viral vectors and cells. Works in close collaboration with the QC manager and senior QC staff to cultivate and enact strategic direction to the GMP area. Under the guidance of senior...
-
Technology Solutions Sales Leader
4 days ago
Columbus, Ohio, United States INDI Staffing Services Full timeAt INDI Staffing Services, we are dedicated to empowering both individuals and organizations globally. Our innovative recruitment specialists connect prominent companies with exceptional talent, creating a vibrant atmosphere where creativity flourishes. Join us in redefining the future of employment.About the Position:We are seeking a Principal Client...
-
Senior Software Engineering Leader
4 days ago
Columbus, Ohio, United States Safelite Group, Inc. Full timeAre you ready to take the next step in your career? At Safelite Group, Inc., we are more than just an auto glass company; we are dedicated to fostering a rewarding career environment while encouraging a balanced life. We strive to be the best workplace you will ever experience. Position Overview The Senior Software Engineering Leader is tasked with shaping...
-
Senior Principal Cloud Product Manager
4 weeks ago
Columbus, Ohio, United States Oracle Full timeJob Description The Oracle Dedicated Cloud Product Management team is looking for an experienced and motivated Senior Principal Product Manager to work across our Dedicated Region Cloud @Customer ) (DRCC) and Oracle Alloy ) offerings and engage with customers to take them to the next level. Your primary objective will be spreadhead the commercial and...
-
Lead Scientist, Manufacturing Science
4 days ago
Columbus, Ohio, United States Forge Biologics Full timeJob OverviewAbout Forge BiologicsAt Forge Biologics, our mission is to facilitate access to transformative gene therapies, turning innovative ideas into reality. We collaborate with pioneers in the gene therapy sector, including scientists, healthcare professionals, biotech and pharmaceutical companies, and patient advocacy groups. Our expertise in gene...
-
Senior Construction Project Leader
4 days ago
Columbus, Ohio, United States Torre Labs Inc. Full timeJob OverviewWe (Torre Labs Inc.) are assisting SIRIS in the search for a qualified candidate to fill the position of Senior Construction Project Leader - Residential.Compensation:USD 140K/year.Location:Columbus, Ohio, United States.About SIRIS:SIRIS is not just a business; it serves as a channel for transformation, a facilitator of aspirations becoming...
-
Principal Water and Wastewater Engineer
4 days ago
Columbus, Ohio, United States HDR Full timeAbout HDR HDR is a leader in providing comprehensive engineering, architectural, environmental, and construction solutions. Renowned for enhancing communities through innovative buildings and sustainable infrastructure, we also deliver a wide array of services. Our diverse teams, comprising scientists, economists, builders, analysts, and artists, form the...
-
Senior Principal Consultant
3 months ago
Columbus, Ohio, United States Oracle Full timeJob Description Do you want to advance your career with the world's first cloud company? Since 1998, Oracle NetSuite has been on a mission to deliver an agile, unified application suite that gives leaders a complete view into their business. Our team is growing, and we're looking for people like you to help us make a global impact. As the leading cloud...
-
Lead Data Scientist
1 month ago
Columbus, Ohio, United States Huntington National Bank Full timeSummary: Our Enterprise Data and Analytics team is growing, and we're looking for an outstanding Lead Data Scientist to join our team. At Huntington, you will leverage machine learning, segmentation, and statistical inference on huge data sets to improve how we understand our customers and the communities we serve. Our goal is to be the Best performing...
-
Optics and Spectroscopy Scientist
4 days ago
Columbus, Ohio, United States Battelle Applied Solutions, LLC Full timeCompany OverviewBattelle Applied Solutions, LLC is a leader in research and development, providing essential services and innovative solutions across various sectors. We value diversity and encourage individuals from all backgrounds to apply.Position SummaryWe are currently seeking a skilled Optics and Spectroscopy Scientist to join our team. This role...
-
Lead Scientist, Manufacturing Science
4 days ago
Columbus, Ohio, United States Forge Biologics Full timeJob OverviewAbout Forge BiologicsAt Forge Biologics, our commitment is to facilitate access to transformative gene therapies, turning innovative concepts into reality. We collaborate with pioneers in the gene therapy sector, including researchers, healthcare professionals, biotech and pharmaceutical companies, and patient advocacy groups. Our expertise in...
-
Principal Engineer
4 weeks ago
Columbus, Ohio, United States TQL Full timeAbout the role:As a Principal Engineer, you will join one of our product lines and work with agile teams responsible for developing web-based versions of our core applications. With your help, our teams will also identify opportunities to trial and deploy new applications and tools.You will use your full-stack software engineering experience to architect and...
-
Senior Structures Program Leader
4 days ago
Columbus, Ohio, United States Johnson, Mirmiran, and Thompson Inc. Full timeJohnson, Mirmiran & Thompson is a vibrant, 100% employee-owned consulting firm comprising over 2,300 professionals, offering a comprehensive range of multi-disciplinary engineering, architecture, information technology, and related services to both public agencies and private clients across the United States. JMT is currently ranked #61 on Engineering...
-
Senior Research Investigator
4 days ago
Columbus, Ohio, United States Ohio State University Wexner Medical Center Full timePosition OverviewThe Ohio State University Wexner Medical Center is seeking a Senior Research Investigator to lead innovative research initiatives within the Department of Microbial Infection and Immunity. This role emphasizes the exploration of biofilms and their implications in dental and orthopedic conditions.Key ResponsibilitiesConduct independent and...
![J&J Family of Companies](https://contents.bebee.com/companies/us/jj-family-of-companies/avatar-ZYjKI.png)
Senior Principal Scientist, Pharmacometrics Leader
2 months ago
Senior Principal Scientist, Pharmacometrics Leader W
Description
Johnson and Johnson is currently seeking a Senior Principal Scientist, Pharmacometrics Leader located in Raritan, NJ or Spring House, PA. Remote work options may be considered on a case-by-case basis and if approved by the company.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.
We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong.
The Senior Principal Scientist, Pharmacometrics role within Clinical Pharmacology & Pharmacometrics (CPP) is to apply and promote clinical pharmacology expertise including the design of clinical pharmacology components of simple and complex clinical studies, pharmacokinetics (PK), pharmacodynamics (PD) analysis and reporting, and application of principles of model-informed drug development (MIDD) to programs in all stages of development, ranging from pre-New Molecular Entity (NME) declaration through post-marketing support. The Senior Principal Scientist CPP Leader is responsible and accountable for developing compound specific Clinical Pharmacology strategy for the development of a compound, including interactions with regulatory agencies and functions as CPP Leader on the Compound Development Teams (CDT) working in collaboration with various stakeholders within the team and within Quantitative Sciences (eg, Statistics, Pharmacometrics). The Senior Principal Scientist CPP Leader can independently execute the day to day operations for the clinical pharmacology aspects of the assigned programs and may provide management directly or indirectly to junior CPP leaders.
Primary responsibilities:
- Devise model informed drug development strategy via application of quantitative methods to integrate knowledge of PK, PD (eg, biomarker, efficacy, and/or safety), patient characteristics, disease states, competitive and landscape to influence go/no go decisions, support patient sub-population, dose and dosage regimen selection, and optimize study designs throughout drug development. Translate quantitative knowledge into strategic opportunities with key stake holders to drive development along the model-informed drug development principles.
- Plan, perform, and/or provide oversight for appropriate analyses (eg population and/or modeling and simulation analysis of PK and/or PD data) of clinical translation, dose/exposure-response relationships, to guide dose regimen and optimize study design.
- Responsible for planning, summarization and interpretation of results of PK and PK/PD analyses with respect to their impact on a development program and clinical use
- Carries out functional responsibilities in accordance to applicable SOPs, regulatory requirements and Johnson & Johnson Credo principles.
- Plan, conduct PK and PK/PD analyses and reporting
- Prepare CP contributions to regulatory documents including briefing books, submission packages, responses to health authority questions, and other regulatory documents. Represent CPP in relevant external regulatory meetings (eg, End of Phase 2, pre-NDA/MAA, Advisory Committee meetings).
- Participate in the evaluation of potential business development opportunities.
- Stay abreast of model informed drug development, analysis methodology and overall drug development process, including regulatory guidance, and methods in modelling and simulation by engaging with the scientific community (eg, publishing, presenting at meetings, participating in special interest groups within professional societies, etc.) and identify new opportunities for applied scientific and technical advancement within the department.
- Apply relevant technical trainings/learnings to daily responsibilities, with focus on value/impact. Where appropriate, serve as mentor/trainer for junior staff.
- Foster working environment that promotes collaboration, innovation, and creativity
- Assist in process improvement initiatives and SOP development where applicable.
Qualifications
Education:
- Master's Degree in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences, with 9 years of experience in pharmaceutical, biomedical, or related field required
- PhD in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences, with 6 years of experience in pharmaceutical, biomedical, or related field preferred
Required:
- Advanced understanding of PK, PD, PK/PD, and/or Translational Medicine
- Experience with modeling tools (eg, NONMEM, R, Gastroplus, Simcyp, Winnonlin, Matlab)
- Understanding of advanced analysis methods (eg, population analysis, PBPK, QSP)
- Demonstrated understanding of overall process of drug development including model informed drug development (MIDD) and the overall pharmaceutical R&D process
- Working knowledge of US, European, and Asian regulatory requirements and guidelines
- Good oral and written communication skills, including ability to interpret PK and PKPD results and prepare presentations to communicate findings effectively and influence stakeholders
- Has established a strong level of expertise and scientific reputation through multiple publications and presentations.
- Up to 10% travel - Domestic & International
Preferred:
- Drug development experience including understanding of disease, patient population, and treatment paradigm.
- Demonstrated ability to apply innovative tools to enable rational and efficient clinical pharmacology strategy of the drug development plan
The anticipated base pay range for this position in the US is $135,000 to $232,300.
The anticipated base pay range for this position in San Francisco Bay Area is $166,000 to $267,145.
The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k).
Employees are eligible for the following time off benefits- Vacation - up to 120 hours per calendar year
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
- Holiday pay, including Floating Holidays - up to 13 days per calendar year
- Work, Personal and Family Time - up to 40 hours per calendar year
For additional general information on company benefits, please go to:
This job posting is anticipated to close on July 17, 2024. The Company may however extend this time-period, in which case the posting will remain available on to accept additional applications.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Primary Location NA-US-New Jersey-Raritan
Other Locations NA-United States, NA-US-Pennsylvania-Spring House
Organization Janssen Research & Development, LLC (6084)
Relocation Eligible: No
Job Function Pharmacokinetics & Pharmacometrics
Req ID: W