Director / Sr. Scientist, Protein Sciences

1 month ago


South San Francisco, United States QLSF Biotherapeutics, Inc. Full time

Director / Sr. Scientist, Protein Sciences


This is a great opportunity to join the highly experienced scientific team at QLSF Biotherapeutics, an innovative immuno-oncology biotech in South San Francisco. We are seeking individual(s) with protein production, purification, and analytical characterization experiences, capable of advancing our pipeline in both drug discovery and development projects. The candidate will be a key contributor in providing oversight for protein science activities for pipeline projects within QLSF Biotherapeutics. The position requires in-depth and hands-on knowledge of protein production, purification, and characterization. Position/Title commensurate with education and experience.


RESPONSIBILITIES

  • Mammalian protein production from scalable transient transfection, through cell harvest, using vacuum and/or depth filtering. Aseptic techniques are a must.
  • High throughput antibody/protein purification using Protein A/G Affinity and other polishing chromatography (IEX, HIC, CEX, SEC, RP) techniques is preferable.
  • Operation and maintaining AKTA chromatographic systems, Agilent HPLC systems, and single use wave bag system (GE/Sartorius).
  • Antibody/protein characterizations using various analytical techniques, such as HPLC-SEC, HPLC-CIEX, SDS-PAGE, spectroscopy, and protein-protein interaction (Biacore/Fortebio). Experience in DSF, differential light scattering, and mass spectrometer is a plus.
  • Develop and optimize monoclonal and multi-specific antibody production and purification.

·        Oversee the protein science group and coordinate with other functional groups to meet timelines.


REQUIRED EXPERIENCE

  • M.S./ Ph.D. in immunology, molecular biology, cell biology, biochemistry, chemical engineering, or other relevant life science disciplines with lab experience. Preferred candidates will have experience working as a scientist in biotech companies.
  • Experience in high throughput transient transfections, filtrations, chromatography by various separation techniques, and analytical characterizations.
  • Execute sound judgment as defined current practices for appropriate actions, understand technical literature for troubleshooting, and demonstrated ability to multitasks and prioritize.
  • Be a good team player and work collaboratively with other scientists.

QLSF Biotherapeutics offers a comprehensive and competitive compensation package, including stock options, paid time off, medical, and 401(k)-retirement savings plan.



  • South San Francisco, United States QLSF Biotherapeutics, Inc. Full time

    Director / Sr. Scientist, Protein SciencesThis is a great opportunity to join the highly experienced scientific team at QLSF Biotherapeutics, an innovative immuno-oncology biotech in South San Francisco. We are seeking individual(s) with protein production, purification, and analytical characterization experiences, capable of advancing our pipeline in both...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...


  • South San Francisco, United States Evercrisp Biosciences Full time

    About Us Evercrisp Biosciences, founded by world-renowned scientists who bring expertise and proprietary technology to the company, is currently operating in stealth mode with a substantial Series A commitment from Apple Tree Partners (ATP) to take the company from discovery to proof of concept. Evercrisp is initially focused on high-confidence,...


  • South San Francisco, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products...

  • Research Scientist

    5 days ago


    San Mateo, California, United States Gilead Sciences Full time

    Job SummaryWe are seeking a highly motivated and detail-oriented Research Scientist to join our Cell Biology team in the Protein Sciences Core. As a Research Scientist, you will contribute to high-impact meaningful projects that will further advance our company's mission to cure cancer.Key ResponsibilitiesDesign and execute experiments to optimize...


  • South San Francisco, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION? If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering...


  • South San Francisco, California, United States Planet Pharma Full time

    Position: Junior Protein Formulation ScientistPlanet Pharma is in search of a Junior Protein Formulation Scientist to enhance their research team. The successful applicant will engage in the formulation of both liquid and lyophilized protein therapeutics, as well as the preparation of formulation and assay buffers, including containers and closures essential...


  • San Diego, United States Treelinebiosciences Full time

    Treeline Biosciences was founded by an experienced team of biopharmaceutical scientists and executives committed to developing new medicines against compelling molecular targets in oncology. As a senior member of the Protein Sciences team, you will play an integral role supporting early-stage discovery programs by collaborating closely with a...


  • San Diego, United States Treeline Biosciences Full time

    Treeline Biosciences was founded by an experienced team of biopharmaceutical scientists and executives committed to developing new medicines against compelling molecular targets in oncology that have proven difficult to drug. We are pursuing a uniquely integrated approach that applies emerging scientific tools and a commitment to building our lead discovery...


  • South San Francisco, California, United States Software Guidance & Assistance, Inc. (SGA, Inc.) Full time

    Company Overview: Software Guidance & Assistance, Inc. (SGA, Inc.) is a distinguished provider of technology and resource solutions, dedicated to addressing complex IT challenges with a personalized approach.Position Summary: We are currently seeking a highly skilled Research Scientist in Protein Engineering to contribute to our innovative projects within...


  • South San Francisco, California, United States Evercrisp Biosciences Full time

    About Evercrisp BiosciencesWe are a cutting-edge biotechnology company dedicated to harnessing the power of CRISPR gene editing to revolutionize genetic medicine. Our team of world-renowned scientists brings expertise and proprietary technology to drive innovation and make a significant impact on human health.The JobWe are seeking a highly motivated and...


  • South San Francisco, United States Software Guidance & Assistance, Inc. (SGA, Inc.) Full time

    Software Guidance & Assistance, Inc., (SGA), is searching for a Research Scientist- Protein biochemistry for a contract assignment with one of our premier Pharmaceutical services clients in South San Francisco, CA.Responsibilities :We are seeking a highly motivated individual to join the Department of Antibody Engineering at the firm as a Research Scientist....


  • South San Francisco, California, United States Software Guidance & Assistance, Inc. (SGA, Inc.) Full time

    Company Overview: Software Guidance & Assistance, Inc. (SGA, Inc.) is a distinguished provider of technology and resource solutions, dedicated to addressing significant IT challenges with a personalized approach.Position Summary: We are currently seeking a driven and enthusiastic Research Scientist specializing in Protein Engineering. This role is integral...


  • South San Francisco, California, United States Orion Group Full time

    Scientist I - Liquid Formulation and Lyophilized Protein Therapeutics Length of Contract: 6 months with possible extensionLocation/Site: ABA-South San Francisco, CAWork Schedule: Monday to Friday 8-5Pay Rate: $41-44/hr (medical benefits available at a cost) Orion Group is seeking a detailed and results-driven Scientist to work with our premiere global...


  • South San Francisco, United States Orion Group Full time

    Scientist I - Liquid Formulation and Lyophilized Protein Therapeutics Length of Contract: 6 months with possible extensionLocation/Site: ABA-South San Francisco, CAWork Schedule: Monday to Friday 8-5Pay Rate: $41-44/hr (medical benefits available at a cost) Orion Group is seeking a detailed and results-driven Scientist to work with our premiere global...


  • South San Francisco, California, United States Lyterian Therapeutics Full time

    At Lyterian Therapeutics, we are committed to developing medicines for patients in need by co-opting physiologically-relevant protein homeostatic mechanisms to regulate genetically-validated targets.As a Post-Baccalaureate in Protein Sciences/Biophysics you will be responsible for producing high-quality protein and protein complex reagents relevant to our...

  • Associate Scientist

    2 weeks ago


    South San Francisco, United States Randstad Life Sciences Full time $30 - $36

    Job DescriptionJob DescriptionImmediate opportunity for an Associate Scientist to work as part of a highly integrated and collaborative team, contributing to diverse functions, depending upon project needs and priority.  With minimal supervision, plans, conducts or monitors experiments, records and organizes data, analyses results, generates robust and...

  • Associate Scientist

    4 weeks ago


    South San Francisco, United States Randstad Life Sciences Full time $30 - $36

    Job DescriptionJob DescriptionImmediate opportunity for an Associate Scientist to work as part of a highly integrated and collaborative team, contributing to diverse functions, depending upon project needs and priority.  With minimal supervision, plans, conducts or monitors experiments, records and organizes data, analyses results, generates robust and...


  • San Diego, California, United States Treelinebiosciences Full time

    About the RoleTreeline Biosciences is a biopharmaceutical company dedicated to developing innovative medicines against challenging molecular targets in oncology. As a senior member of our Protein Sciences team, you will play a critical role in supporting early-stage discovery programs by collaborating closely with a cross-functional team of scientists to...


  • San Francisco, California, United States Nurix Therapeutics Full time

    PositionWe are seeking a skilled and motivated Scientist to join Nurix's DEL & Protein Sciences team. Nurix is devoted to unlocking the therapeutic potential of the ubiquitin proteasome system (UPS) in the areas of oncology and immuno-oncology, by utilizing the mechanistic and structural insights to guide drug discovery efforts. The successful candidate will...