Director / Sr. Scientist, Protein Sciences
1 month ago
Director / Sr. Scientist, Protein Sciences
This is a great opportunity to join the highly experienced scientific team at QLSF Biotherapeutics, an innovative immuno-oncology biotech in South San Francisco. We are seeking individual(s) with protein production, purification, and analytical characterization experiences, capable of advancing our pipeline in both drug discovery and development projects. The candidate will be a key contributor in providing oversight for protein science activities for pipeline projects within QLSF Biotherapeutics. The position requires in-depth and hands-on knowledge of protein production, purification, and characterization. Position/Title commensurate with education and experience.
RESPONSIBILITIES
- Mammalian protein production from scalable transient transfection, through cell harvest, using vacuum and/or depth filtering. Aseptic techniques are a must.
- High throughput antibody/protein purification using Protein A/G Affinity and other polishing chromatography (IEX, HIC, CEX, SEC, RP) techniques is preferable.
- Operation and maintaining AKTA chromatographic systems, Agilent HPLC systems, and single use wave bag system (GE/Sartorius).
- Antibody/protein characterizations using various analytical techniques, such as HPLC-SEC, HPLC-CIEX, SDS-PAGE, spectroscopy, and protein-protein interaction (Biacore/Fortebio). Experience in DSF, differential light scattering, and mass spectrometer is a plus.
- Develop and optimize monoclonal and multi-specific antibody production and purification.
· Oversee the protein science group and coordinate with other functional groups to meet timelines.
REQUIRED EXPERIENCE
- M.S./ Ph.D. in immunology, molecular biology, cell biology, biochemistry, chemical engineering, or other relevant life science disciplines with lab experience. Preferred candidates will have experience working as a scientist in biotech companies.
- Experience in high throughput transient transfections, filtrations, chromatography by various separation techniques, and analytical characterizations.
- Execute sound judgment as defined current practices for appropriate actions, understand technical literature for troubleshooting, and demonstrated ability to multitasks and prioritize.
- Be a good team player and work collaboratively with other scientists.
QLSF Biotherapeutics offers a comprehensive and competitive compensation package, including stock options, paid time off, medical, and 401(k)-retirement savings plan.
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Director / Sr. Scientist, Protein Sciences
1 month ago
South San Francisco, United States QLSF Biotherapeutics, Inc. Full timeDirector / Sr. Scientist, Protein SciencesThis is a great opportunity to join the highly experienced scientific team at QLSF Biotherapeutics, an innovative immuno-oncology biotech in South San Francisco. We are seeking individual(s) with protein production, purification, and analytical characterization experiences, capable of advancing our pipeline in both...
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