Current jobs related to Associate Scientist/Scientist, In vivo pharmacology - Cambridge - Third Rock Ventures
-
cambridge, United States Third Rock Ventures Full timeAssociate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...
-
Principal Scientist
4 weeks ago
Cambridge, United States Delphia Therapeutics Full timePrincipal Scientist / Associate Director, In vivo PharmacologyAbout Us:Delphia is a biotechnology company on a mission in the service of patients to pioneer an entirely new field of cancer biology, Activation Lethality, that targets cancer’s vulnerability to oncogene overactivation. Together, we are working to advance first-in-class targeted cancer...
-
Principal Scientist
2 months ago
Cambridge, United States Delphia Therapeutics Full timePrincipal Scientist / Associate Director, In vivo PharmacologyAbout Us:Delphia is a biotechnology company on a mission in the service of patients to pioneer an entirely new field of cancer biology, Activation Lethality, that targets cancer’s vulnerability to oncogene overactivation. Together, we are working to advance first-in-class targeted cancer...
-
Principal Scientist
4 weeks ago
cambridge, United States Delphia Therapeutics Full timePrincipal Scientist / Associate Director, In vivo PharmacologyAbout Us:Delphia is a biotechnology company on a mission in the service of patients to pioneer an entirely new field of cancer biology, Activation Lethality, that targets cancer’s vulnerability to oncogene overactivation. Together, we are working to advance first-in-class targeted cancer...
-
Principal Scientist
2 months ago
Cambridge, United States Delphia Therapeutics Full timePrincipal Scientist / Associate Director, In vivo PharmacologyAbout Us:Delphia is a biotechnology company on a mission in the service of patients to pioneer an entirely new field of cancer biology, Activation Lethality, that targets cancer’s vulnerability to oncogene overactivation. Together, we are working to advance first-in-class targeted cancer...
-
Principal Scientist
1 week ago
Cambridge, MA, United States Delphia Therapeutics Full timePrincipal Scientist / Associate Director, In vivo PharmacologyAbout Us:Delphia is a biotechnology company on a mission in the service of patients to pioneer an entirely new field of cancer biology, Activation Lethality, that targets cancer’s vulnerability to oncogene overactivation. Together, we are working to advance first-in-class targeted cancer...
-
Principal Scientist
4 weeks ago
Cambridge, Massachusetts, United States Delphia Therapeutics Full timeAbout Delphia TherapeuticsDelphia Therapeutics is a biotechnology company pioneering a new field of cancer biology, Activation Lethality, to develop targeted cancer medicines that provide better outcomes for patients.The RoleWe are seeking a Principal Scientist / Associate Director, In Vivo Pharmacology to join our team and lead the development and execution...
-
Senior Scientist In Vivo Discovery
4 weeks ago
Cambridge, Massachusetts, United States Editas Medicine Full timeAbout the RoleWe are seeking a highly motivated and skilled Associate Scientist II to join our In Vivo Discovery team at Editas Medicine. As a key member of our team, you will be responsible for developing and optimizing molecular assays for evaluating editing outcomes of CRISPR-based therapeutics in an in vivo context.Key Responsibilities:Development and...
-
Cambridge, Massachusetts, United States Flagship Pioneering, Inc. Full timeWe are seeking a highly motivated Research Associate to join our team at Flagship Pioneering, Inc. in the role of Senior Research Associate/Associate Scientist, Platform.The successful candidate will be responsible for driving in vivo studies using our novel nucleic acid therapeutics platform.Key responsibilities include:Execution and analysis of animal...
-
Scientist/Senior Scientist
4 weeks ago
cambridge, United States GC Therapeutics Full timeScientist/Senior Scientist - In Vivo Biology (Neuroscience)Company OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in...
-
Scientist/Senior Scientist
2 months ago
Cambridge, United States GC Therapeutics Full timeScientist/Senior Scientist - In Vivo Biology (Neuroscience)Company OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in...
-
Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Description SummaryNovartis Group Companies is seeking a highly motivated Research Scientist to join our Cell Pharmacology team. The successful candidate will contribute to advancing our understanding of disease biology, target identification efforts, and the discovery and optimization of new drugs for CVM. The role involves collaboration with research...
-
Cambridge, Massachusetts, United States Flagship Ventures Full timeJoin Our Team as a Sr. Research Associate of In Vivo PharmacologyWe are seeking a highly skilled and motivated Sr. Research Associate of In Vivo Pharmacology to join our team at Flagship Pioneering. As a key member of our research team, you will be responsible for conducting in vivo studies to evaluate the efficacy of novel therapies in animal models.About...
-
Sr. Associate Scientist, DMPK In-Vivo
4 days ago
Cambridge, United States Biogen Full timeJob DescriptionAbout This RoleBiogen is seeking a highly motivated scientist to join the Drug Metabolism and Pharmacokinetics (DMPK) department at our Kendall Square site in Cambridge, Massachusetts. The role requires hands-on experience in conducting in-vivo studies in rodents, and basic familiarity with the concepts of pharmacokinetics (PK). The ideal...
-
Scientist II
1 month ago
Cambridge, United States Mindlance Full timeJob Title Scientist IIDuration: 6 months + with possible extensionSite: Cambridge, MADescription:We are seeking a highly motivated and creative scientist to join Immunology and Inflammation Therapeutic Area (I&I TA) located in Cambridge, MA. This position will work with the Type 2 Inflammation research team towards increasing our biological understanding of...
-
Senior Research Scientist
3 weeks ago
Cambridge, Massachusetts, United States Nava Therapeutics Full timeSenior Scientist – Lipid Nanoparticle (LNP) DeliveryNava Therapeutics is a rapidly growing, early-stage company that is developing cutting-edge, high-throughput technologies to discover and advance novel delivery strategies for nucleic acid therapeutics. Our mission is to make a difference in the daily lives of patients through our clinical impact.We offer...
-
Scientist
3 months ago
Cambridge, United States GC Therapeutics Full timeScientist / Senior Scientist – Computational BiologyCompany OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor...
-
Research Associate, In Vivo Biology
2 months ago
Cambridge, United States GC Therapeutics Full timeResearch Associate, In Vivo BiologyCompany OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s...
-
Research Associate, In Vivo Biology
3 months ago
Cambridge, United States GC Therapeutics Full timeResearch Associate, In Vivo BiologyCompany OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s...
-
Research Associate, In Vivo Biology
3 months ago
cambridge, United States GC Therapeutics Full timeResearch Associate, In Vivo BiologyCompany OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s...
Associate Scientist/Scientist, In vivo pharmacology
1 month ago
Associate Scientist/Scientist, In vivo pharmacology
A well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo pharmacology representative for discovery-stage pipeline program(s) focused on antibody-driven diseases. The role will work collaboratively with the Biology team lead(s) to contribute to lead characterization and development candidate selection. The Associate Scientist/Scientist will aid in the management of external and internal in vivo pharmacology studies, including model development and characterization. The ideal candidate is an expert lab-based in vivo pharmacologist with a background in immunology and biologics drug discovery.
Responsibilities:
- Serve as functional team lead for pre-clinical pipeline program(s) and work collaboratively/partner with peer team leads to advance program(s) to IND
- Design and manage in vivo biology functional experiments that support preclinical drug discovery including PK/PD analysis, mechanism of action studies, and disease modeling
- Assist in managing internal in vivo pharmacology capabilities at a shared vivarium space, including some animal handling/sample collection
- Independently develop and execute quantitative assays for the analysis/characterization of ex vivo samples (ELISA, flow cytometry)
- Manage out-sourced CRO-based workflows, including study design and data analysis
Required qualifications and experience:
- Ph.D. in relevant scientific area, such as immunology, cell/molecular biology with 0-3 years in Biotech/Pharma pharmacology group or BA/BS in a relevant scientific area with 8+ years experience in Biotech/Pharma industry within in vivo pharmacology
- Extensive experience in the design and execution of in vivo studies, particularly in assessing pharmacokinetics/pharmacodynamics (biologics experience preferred)
- Experience in ex vivo sample analysis and data interpretation (immunophenotyping, ELISA)
- Capacity to work within a dynamic matrix environment, with strong contribution to project strategy and execution
- Excellent communication, presentation, and inter-personal skills; superb organizational and problem-solving skills
- Contribution to the design and execution of IND-enabling in vivo studies preferred
