Senior Scientist, Immunology Discovery

6 days ago


Cambridge, United States Simcere Zaiming Full time

Senior Scientist (Preclinical-Autoimmunity)

Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and troubleshooting of experimental approaches required for development of novel therapies for autoimmune diseases. This is an exciting opportunity to be part of a highly collaborative team and to apply your knowledge and experience to develop innovative targets from early discovery to IND-enabling studies using in vitro and in vivo humanized experimental models.

In this position you will be required to:

  • Apply your deep knowledge in immunology, inflammation, and autoimmunity in leading drug discovery programs from target validation to candidate nomination.
  • Design, execute, analyze, and troubleshoot immunological functional assays (multi-color flow cytometry; bioanalytical measurement assays (ELISA, MSD); immune cells interaction, activation, migration, suppression, and proliferation; autoimmune animal models).
  • Collaborate with cross-functional teams to advance the company’s pipeline.
  • Suggest and promote novel therapeutic targets and technologies.
  • Be informed of the scientific advancement in your area of expertise.
  • Interact with different scientists across the company and partners.
  • Provide guidance to junior members of the team.
  • Prepare reports and research documents for publishing, patent, and IND filings.
  • Be able to adapt to changing priorities and deadlines.

Qualifications and experience:

  • A PhD degree in immunology, cellular biology, biochemistry, or a related field with at least 5 years of relevant experience.
  • Strong scientific background in understanding pathways involved in autoimmunity and inflammation.
  • Demonstrated experience in execution, analysis, and troubleshooting of immunological assays.
  • Skilled in cellular and molecular immunology techniques.
  • Experience working with mouse autoimmune models.
  • Strong analytical and problem-solving skills.
  • Effective communicator and multitasker with strong record-keeping and organizational skills.
  • Demonstrated a strong scientific record (publications, presentations, and/or patents).
  • Self-motivated, team- and goal-oriented scientist with excellent oral and written communication skills.

What we offer at Simcere:

  • An innovation-driven culture that puts science at the forefront of everything we do.
  • A dynamic, diverse, and inclusive team of experienced scientists applying their skills to some of the most impactful problems in human health.
  • Welcoming and collaborative working environment.
  • Competitive compensation and benefits.



  • Cambridge, United States Simcere Zaiming Full time

    Senior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...


  • Cambridge, United States UCB Full time

     Make your mark for patients To strengthen our Discovery Sciences and Protein Sciences teams in our Boston hub in Cambridge, MA, USA, we are looking for a talented individual to fill the position of: Scientist or Senior Scientist.  As (Senior) Scientist, you will contribute to a scientific team as protein biochemist and cellular biologist. You...


  • Cambridge, United States UCB Full time

     Make your mark for patients To strengthen our Discovery Sciences and Protein Sciences teams in our Boston hub in Cambridge, MA, USA, we are looking for a talented individual to fill the position of: Scientist or Senior Scientist.  As (Senior) Scientist, you will contribute to a scientific team as protein biochemist and cellular biologist. You...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    Immunology Research ScientistFlagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. We are seeking a highly skilled PhD level Principal Scientist with proven experience in immunology and preclinical research to join our team.Key...


  • Cambridge, Massachusetts, United States Generation Bio Full time

    Immunology Research Scientist OpportunityGeneration Bio is a pioneering biotech company innovating non-viral genetic medicines to treat rare and prevalent diseases. We are seeking an experienced Immunology Research Scientist to join our team and contribute to the development of our cell-targeted lipid nanoparticle (ctLNP) delivery platform.Key...


  • Cambridge, Massachusetts, United States Novartis Group Companies Full time

    About the Role:The Novartis Group of Companies is seeking a highly skilled and experienced Senior Principal Scientist to join our team in Cambridge, MA. As a key member of our dynamic and multi-disciplinary team, you will play a critical role in developing and applying in vivo models to evaluate novel cancer therapies in the early-stage drug discovery...


  • Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full time

    About the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    Transforming Drug Discovery with Flagship PioneeringAt Flagship Pioneering, we are dedicated to transforming drug discovery by leveraging deep biological insights and cutting-edge scientific innovations. Our mission is to deliver breakthrough therapies that address critical unmet medical needs.Job SummaryWe are seeking an experienced and highly motivated...


  • Cambridge, Massachusetts, United States SIMCERE OF AMERICA, INC Full time

    Simcere of America, Inc. is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are seeking a highly skilled and innovative Associate Scientist to enhance our preclinical research division.Key Responsibilities:Design and execute cell-based assays to identify potential targets, utilizing a range of...


  • Cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...


  • Cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...


  • Cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...


  • Cambridge, Massachusetts, United States Bristol-Myers Squibb Full time

    Job SummaryBristol Myers Squibb is seeking a highly skilled and experienced Medical Director, Early Clinical Development Immunology to join our team. As a key member of our Early Clinical Development function, you will be responsible for leading the development of clinical studies and research plans in support of asset strategy. You will work closely with...


  • Cambridge, Massachusetts, United States Flagship Ventures Full time

    Job SummaryWe are seeking an experienced and highly motivated Principal Scientist with a proven track record of early discovery and characterization of novel biologics to join our team at Flagship Ventures.Key ResponsibilitiesConduct impactful research and experiments for biologics discovery and advancement of our platform.Influence the direction of...

  • Scientist

    3 days ago


    Cambridge, United States Randstad Life Sciences US Full time

    Scientist I6 MonthsCambridge, MA Job description:We are currently seeking a highly motivated and passionate scientist in cellular immunology to join our team in Immunology Discovery department based in Cambridge MA.The candidate will focus on making therapeutic molecules using recombinant DNA technology, expression/purification of recombinant proteins,...

  • Scientist

    3 days ago


    Cambridge, United States Randstad Life Sciences US Full time

    Scientist I6 MonthsCambridge, MA Job description:We are currently seeking a highly motivated and passionate scientist in cellular immunology to join our team in Immunology Discovery department based in Cambridge MA.The candidate will focus on making therapeutic molecules using recombinant DNA technology, expression/purification of recombinant proteins,...


  • Cambridge, United States Third Rock Ventures Full time

    Associate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...


  • Cambridge, United States Third Rock Ventures Full time

    Associate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...


  • Cambridge, United States Third Rock Ventures Full time

    Associate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...


  • Cambridge, Massachusetts, United States CAMP4 Therapeutics Full time

    About the RoleCAMP4 Therapeutics is seeking a highly skilled and experienced scientist to lead our Discovery team in driving cutting-edge projects from target selection through development candidate selection. As a Principal Scientist, Discovery, you will be responsible for driving innovative science to develop antisense oligonucleotide drugs against...