Senior Research Scientist

1 week ago


Cambridge, Massachusetts, United States SIMCERE OF AMERICA, INC Full time

Simcere of America, Inc. is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are seeking a highly skilled and innovative Associate Scientist to enhance our preclinical research division.

Key Responsibilities:

  • Design and execute cell-based assays to identify potential targets, utilizing a range of molecular biology techniques tailored to oncology or immunologic disease
  • Develop and conduct genomic, protein, and cell-based assays for target validation, discovery elucidation, and mechanism of action analysis
  • Perform sophisticated multi-color flow cytometry to characterize immune and cancer cells
  • Execute bioanalytical assays, including ddPCR, ELISA, MSD, and Western Blot, for precise quantification of target proteins
  • Conduct cytotoxicity assay/proliferation assay to examine the functionality of the targets
  • Independently design experiments, analyze results, and present findings with minimal oversight
  • Collaborate with interdisciplinary teams to propel Simcere's pipeline forward
  • Stay abreast of scientific developments within your field of expertise

Requirements:

  • A Bachelor's or Master's degree in Cellular Biology, Immunology, Oncology, or a related discipline, accompanied by a minimum of two years' pertinent experience, preferably from the Industry
  • Proficiency in molecular biology techniques such as cloning, transformation, transfection, transduction, qPCR, gene editing-CRISPR, RNAi, RNA sequencing, NGS, and Western blotting
  • Expertise in cell culture practices, including handling primary cells (e.g., human T and myeloid cells) and established cell lines
  • A robust foundation in conducting, analyzing, and troubleshooting cellular assays
  • Training in various cellular assays like flow cytometry, cell proliferation, and immunological assays
  • Exceptional analytical and problem-solving capabilities
  • Strong communication skills, adept at multitasking, with a commitment to meticulous record-keeping and organization
  • A self-starter with a team-centric and results-oriented mindset

What We Offer:

  • A culture fueled by innovation, placing science at the heart of our operations
  • A vibrant, diverse team of seasoned scientists dedicated to addressing some of the most pressing challenges in human health
  • A competitive compensation and benefit package, including salary, comprehensive health, dental, vision coverage, long and short-term disability, and 401k match

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