Analytical Chemist

2 days ago


Cambridge, Massachusetts, United States Integrated Resources, Inc ( IRI ) Full time
Job Summary:

We are seeking a highly skilled Analytical Chemist to join our Formulations Sciences group of Pharmaceutical Sciences. As a key member of our team, you will contribute to the execution of laboratory activities related to the transition of Client small molecule compounds from Discovery into Development in support of pre-clinical and clinical programs.

Key Responsibilities:
  • Prepare buffers and common lab solutions
  • Execute analytical experiments with XRPD, DSC, TGA, DVS, SEM, optical microscopy and UPLC/HPLC (Empower)
  • Screen excipients/formulation vehicles for solubility and stability to optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies
  • Perform drug substance and formulation stability studies to ensure optimal formulation design
  • Coordinate vehicle/formulation preparations for in vivo studies
  • Execute dissolution studies (Distek and Pion μDISS) to support formulation development and FIH development
  • Maintain an accurate, timely, and compliant laboratory notebook
Requirements:
  • B.S. degree in chemistry, analytical chemistry, pharmaceutics, chemical engineering or material sciences
  • 2+ years' experience working in pharmaceutical sciences (pre formulation, analytical or formulation development)
  • Experience in the Discovery and Development interface [desirable not required]
  • Experience working with common excipients and volumetric glassware
  • Proficiency with UPLC/HPLC and Empower Software
  • Some knowledge of and interest in learning more about small molecule and pre-clinical formulation development
Capabilities:
  • Ability to effectively prioritize and manage multiple tasks and compounds
  • Self-motivated and willing to "learn on the job" and ask for assistance when needed
  • At home in a results-driven, highly accountable environment where you can make a clear impact
  • A team player, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner

Integrated Resources, Inc (IRI) is an equal opportunity employer and welcomes applications from diverse candidates. All applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.


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