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Analytical Chemist

2 months ago

cambridge, United States Randstad Life Sciences US Full time

Title: Analytical Chemist

Contract: 6 Months with possible extension

Location: Cambridge, MA


Note: Only USA Citizens for this role and no relocation.


The ideal candidate will have a Master’s degree in Analytical Chemistry, Organic Chemistry, Physical Chemistry, Pharmaceutical Sciences, Life Sciences, or Engineering, along with at least 2 years of experience in the biotech industry. They should have hands-on experience with chromatographic techniques such as Cation Exchange Chromatography (CEX), Size Exclusion Chromatography (SEC), and Reversed-Phase Liquid Chromatography (RPLC). Proficiency with the Waters Empower Chromatography Data System (CDS) for data acquisition, processing, and management is essential, as is experience working with biologics like antibodies and peptides. This individual will support chemists by troubleshooting instrumentation and analytical methods, analyzing samples using various chromatographic techniques, and optimizing methods for accuracy and reliability. Additionally, they will use the Waters Empower CDS to manage chromatographic data and enhance laboratory workflows. The ideal candidate should demonstrate strong problem-solving skills, be adept at overcoming complex analytical challenges, and take a proactive approach to supporting and improving laboratory operations.


  • Basic Qualifications
  • 0+ Years w/ Relevant PhD OR equivalent (where applicable) 2+ Years w/ Relevant MS OR equivalent 4+ Years w/ Relevant BS OR equivalent Advanced and proficient understanding and use of technical principles, theOR ies, and concepts to perform expansive range of wOR k in a role.Basic knowledge of related and adjacent disciplinary areas.
  • Top 3 Must Have Skill Sets:
  • Experience with operation, maintenance, and troubleshooting of laboratory equipment and instrumentation, especially chromatographic (e.g. liquid chromatography) and spectroscopic instruments (e.g. mass spectrometry)
  • Hands on experience in Waters Empower CDS
  • Experience in synthetic peptide and/or peptide antibody conjugates including theoretical knowledge, research, and hands-on experience to support process development/scale up activities and formulation development.




Summary

  • Company is currently seeking an Analytical Chemist in our Pivotal Attribute Sciences Department in Cambridge, MA. This team plays a crucial role in pivotal phase analytical support, including product development support, testing of drug substances and drug products.
  • The role will work closely with a team of analysts and scientists responsible for the technical aspects of developing analytical tools to gain understanding of key quality attributes in product and process for late phase synthetic small molecule, synthetic peptide and/or antibody peptide conjugates. The Scientist will integrate and optimally utilize platform and in-depth product attribute knowledge to advance Company products and ensure success through pivotal clinical phases to marketing authorization application.

Responsibilities

  • Let’s do this Let’s change the world In this vital role you will integrate and optimally utilize platform and in-depth product attribute knowledge to advance Company products and ensure success through pivotal clinical phases to marketing authorization application.
  • Regularly perform and adequately document routine maintenance of the HPLC instrument.
  • Ensure consumables and supplies are properly maintained and readily available
  • Hand-on experience in sample preparation and analysis of synthetic in-process samples, lot release samples, and drug product formulations using primarily chromatographic and spectroscopic techniques.
  • Organize and document analytical data under Good Documentation Practice using electronic laboratory notebook system.
  • Perform all duties in accordance with established quality protocols and standard operating procedures (SOPs)
  • Provide general laboratory support and other responsibilities as assigned by the Supervisor.

Preferred Qualifications:

  • Master’s degree in Analytical Chemistry, Organic Chemistry, Physical, Pharmaceutical, Life Sciences or Engineering
  • Hands on experience in chromatographic techniques such as: CEX, SEC and RPLC
  • Experience in synthetic peptide and/or peptide antibody conjugates including theoretical knowledge, research, and hands-on experience to support process development/scale up activities and formulation development.
  • Experience with operation, maintenance, and troubleshooting of laboratory equipment and instrumentation, especially chromatographic (e.g. liquid chromatography) and spectroscopic instruments (e.g. mass spectrometry).
  • Experience in laboratory settings within the pharmaceutical or biotech industry
  • Technical aptitude for identification, development, and implementation of novel analytical technologies