Senior Immunology Program Lead

1 week ago


Branford, Connecticut, United States EVOLVEIMMUNE THERAPEUTICS, Inc. Full time
About Us

EvolveImmune Therapeutics, Inc. is a pioneering company in the field of immune-oncology. We are committed to developing novel therapies that optimize anti-tumor immunity.

Job Summary

We are seeking an experienced Senior Immunology Program Lead to join our Immunobiology team. The ideal candidate will have a strong background in T cell engager drug development and experience in managing teams.

Key Responsibilities
  • Design and implement functional ex vivo and in vivo studies to evaluate protein therapeutics and guide data-driven decisions for lead and candidate selection.
  • Oversee immune co-culture assays, including mixed lymphocyte reaction and T cell-tumor cell cytotoxicity assays, to identify phenotypes associated with genetic modifications.
  • Develop target expression assessment and functional studies with patient samples to delineate differentiation opportunities for emerging and selected lead molecules.
  • Collaborate with the in vivo pharmacology team to design studies evaluating drug candidate characteristics such as distribution properties, pharmacokinetic profile, early safety readouts, and disease state modifications.
  • Mentor and manage team members to ensure high-quality work and effective communication.
Requirements
  • PhD in Immunology or related field with postdoctoral experience and 4+ years of industry experience.
  • Experience in T cell engager immunotherapies, including technical expertise in assaying tumor killing, cytokine release, and immune cell function ex vivo and in vivo.
  • Proven ability to manage drug discovery and development teams, demonstrated by a strong publication, patent, and/or drug development record in T cell engager therapies.
What We Offer

A competitive compensation package based on experience level, with a salary range of $160,000 - $220,000 per annum.



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