Lead Process Systems Engineer, Cell Therapy

2 weeks ago


Devens, Massachusetts, United States Bristol-Myers Squibb Full time
About Us

At Bristol Myers Squibb, we redefine the meaning of work. Here, every day presents an opportunity to engage in challenging and impactful projects that significantly affect patients' lives.

From enhancing production processes to pioneering advancements in cell therapy, our work is transformative for both our patients and our employees.

We provide an environment where you can flourish and advance your career through unique opportunities, working alongside diverse and high-performing teams.

Position Overview:


The Senior Specialist, Process Systems Engineer is responsible for contributing to the design and development of electronic Process Systems, including DeltaV, OSI Pi, electronic batch records (MES), and process monitoring systems. This role involves collaboration with Digital Plant, IT, Manufacturing Operations, and subject matter experts to implement process modifications.

The ideal candidate will possess strong project management capabilities and the ability to coordinate with various stakeholders, demonstrating leadership, enthusiasm, and a commitment to scientific excellence.

Key Responsibilities:

  • Utilize manufacturing process expertise and technical knowledge of process systems during change management initiatives.
  • Revise Functional Specifications for process systems, ensuring consistent execution of modifications and compliance with governing documents.
  • Collaborate with Manufacturing, Digital Plant, IT, Validation, Quality, and MSAT to ensure timely closure of change initiatives.
  • Manage the lifecycle of process system changes effectively.
  • Gather user requirements for change development from site functional teams, including manufacturing, engineering, warehouse, and quality assurance.
  • Demonstrate understanding of DeltaV and MES library objects to guide changes to related systems.
  • Create documentation to support the qualification of DeltaV and MES recipes, including test scripts and functional specifications.
  • Conduct testing of changes in the development environment to verify functionality.
  • Generate reports or metrics using reporting software.
  • Employ creative problem-solving techniques.
  • Provide technical support for manufacturing operations, investigations, and change controls as a process system expert.
  • Foster strong collaboration within the plant and across the network.
  • Build trust and effective relationships with peers and stakeholders.
  • Perform additional tasks as assigned.
Qualifications & Experience:

  • Bachelor’s Degree in a relevant field from an accredited institution (science or engineering preferred).
  • A minimum of 2 years of relevant experience, ideally in the pharmaceutical, biotechnology, or cell therapy manufacturing sectors.
  • Familiarity with DeltaV, Syncade MES, or other process automation systems is highly desirable.
  • Experience in cell therapy, biologics, or vaccine manufacturing support, tech transfer, and validation is essential.
  • Strong project management skills are required, with at least 1 year of experience in project coordination and cross-functional team leadership preferred.
  • At least 1 year of experience supporting Delta V, Syncade MES, or other process automation software is advantageous.
Working Conditions:

  • The incumbent will be required to adhere to gowning protocols to access classified manufacturing areas.
  • Flexibility to work extended hours or modified schedules as necessary for 24/7 manufacturing operations is expected.


This job description outlines the general nature and level of work expected from the individual in this position. The primary duties and responsibilities are intended to encompass essential functions of the role.

Additional responsibilities may be assigned as deemed necessary by management.



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