Principal Scientist Medicinal Chemistry
7 days ago
We are seeking a highly skilled and motivated medicinal chemist to join our team as a Principal Scientist in Medicinal Chemistry. The successful candidate will have a strong background in organic chemistry and a proven track record of designing and executing complex syntheses.
Key Responsibilities- Design and execute multistep syntheses of complex organic molecules using modern organic chemistry techniques.
- Develop and implement innovative synthetic strategies to address emerging SAR data.
- Collaborate with cross-functional teams to advance discovery programs and achieve critical milestones.
- Lead or co-lead multi-disciplinary discovery programs and advance them to critical milestones.
- Develop and maintain a strong understanding of medicinal chemistry principles, synthetic methods, and reaction mechanisms.
- Bachelor's Degree and 8+ years of academic or industry experience.
- OR Master's Degree and 6+ years of academic or industry experience.
- OR Ph.D. and 4+ years of academic or industry experience.
- Ph.D. with 4+ years of industry relevant experience.
- Demonstrated record of productivity in organic or medicinal chemistry research as evidenced by publications and/or patents.
- Independent, creative target design and high level of synthetic productivity applying modern synthetic methods with strong chemistry problem-solving skills.
- A strong commitment to experimental work is expected, demonstrated by an ability to carry out multi-step syntheses and state-of-the-art purifications, with spectroscopic characterizations of novel organic compounds (NMR, LC-MS, HPLC, etc.).
- Proficient with Chemdraw, and other medicinal chemistry-related software.
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy.
- Emerging understanding of the drug discovery and development process.
- A naturally collaborative and self-motivated style is necessary to work effectively in a fast-paced, highly integrated team environment.
- Excellent written and oral communication skills, demonstrated ability to write peer reviewed quality work or invention disclosures for patent applications, and able to present the rationale, key data, issues and accomplishments department wide.
- Uniquely interesting work that transforms the lives of patients and the careers of those who do it.
- A diverse, high-achieving team united by a common mission.
- A broad range of disciplines to enable a robust pipeline of drug candidates aimed at serious diseases.
- A collaborative and self-motivated work environment.
- Excellent compensation and benefits package, including a range from $121,000 - $167,270, plus incentive cash and stock opportunities (based on eligibility).
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