Postdoctoral Research Associate

1 day ago


New York, New York, United States Rockefeller University Full time
Postdoctoral Position in Molecular Biology

The Laboratory of Molecular Biology at The Rockefeller University is seeking a highly motivated and accomplished postdoctoral researcher to join our team. Our laboratory is dedicated to understanding the genes, circuits, cells, and macromolecular assemblies that contribute to the function of the mammalian brain and its dysfunction in disease.

Research Focus

We are particularly interested in the selective vulnerability and degeneration of upper motor neurons in amyotrophic lateral sclerosis (ALS). Our research aims to elucidate cell type-specific phenotypes during disease progression in preclinical mouse models and postmortem human tissue. By contrasting vulnerable and resilient neuronal populations as well as non-neuronal cells, we hope to identify novel disease mechanisms and potential entry points for therapeutic intervention.

Responsibilities
  • Isolate and profile RNA from human and mouse tissue using advanced molecular profiling methods
  • Purify and profile cell type-specific mitochondria from preclinical models
  • Perform multi-omics analysis of sequencing and proteomics data sets
  • Conduct anatomical analyses using ISH, IHC, viral tracing, and functional mapping
Qualifications

The ideal candidate will have a Ph.D. in neuroscience or a related field and prior research experience in molecular or cellular biology. Preference will be given to those with familiarity with next-generation sequencing, quantitative analysis of sequencing data, animal models of CNS disorders, neuroanatomy, and immunohistological methods. Candidates must demonstrate a strong track record of research productivity, scientific rigor, excellent communication skills, and the ability to work independently and as part of a team.

The Rockefeller University is an equal opportunity employer and welcomes applications from diverse candidates. The salary of the finalist selected for this role will be set based on various factors, including qualifications, experience, and organizational budgets.



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