Senior Computational Biologist

3 weeks ago


Cambridge, Massachusetts, United States Sana Biotechnology, Inc. Full time

About Sana Biotechnology, Inc.

Sana Biotechnology, Inc. is a leader in the field of computational biology. Our team is growing, and we are seeking talented individuals who share our passion for developing novel cell therapies.

Job Summary:

We are seeking a highly skilled Principal Bioinformatician to join our team. As a Principal Bioinformatician, you will be responsible for designing experiments, analyzing data, and providing interpretable results to aid in hypothesis generation. You will work closely with our team to develop new methodologies and workflows, and collaborate with other groups to provide reproducible, tested, and robust analyses.

Responsibilities:

  • Partner with the beta islet group to design studies, answer biological questions, and analyze cell differentiation data.
  • Derive insights from transcriptomic and other omics datasets, including scRNA-seq, bulk RNA-seq, and snRNA-seq that enable therapeutic development.
  • Communicate to a broad audience with a range of technical, analytical, and biological expertise and present results at group meetings.
  • Collaborate with Computational Biology and Computational Engineering groups to provide reproducible, tested, and robust analyses.

Requirements:

  • A D. in computational biology, genetics, bioinformatics, statistics, or related discipline with 5+ years of industry or relevant academic experience, or M.Sc. with 10+ years or equivalent combination of education/work experience.
  • Domain experience in stem cell differentiation and engraftment experiments, especially islet beta cells or other endocrine cell lineages.
  • Knowledge of mammalian cell differentiation and methods to assess purity and stability of iPSC generated cell lines.
  • Proficiency in Python and R, Unix/Linux, and HPC systems; familiarity with testing frameworks for assuring code correctness.
  • Strong scientific background including an understanding of molecular biology, cell biology, and genomics resources.

What We Offer:

  • The base pay range for this position is expected to be between $175,000 and $205,000/year.

How We Work Together for Patients:

  • Lead from every seat - we seek to understand, act with honesty, and engage in the crucial conversations.
  • Thrive as a team - we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity.
  • Make it happen - we value vigorous debate, alignment around our decisions, and resilient execution.

Get to Know Us:

Sana Biotechnology, Inc. believes that a diverse workforce strengthens us as a company and helps us achieve our mission to meaningfully change the outcome of many human diseases. Our goal is to create a workplace where everyone feels valued, respected, and empowered to contribute their best work.



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