Principal Scientist

4 weeks ago


Cambridge, Massachusetts, United States Novartis Group Companies Full time
About the Role:

We are seeking a highly motivated and experienced Principal Scientist to join our interdisciplinary team at Novartis. As a key member of our team, you will be responsible for proposing, designing, and evaluating novel assays and chemotypes to tackle longstanding challenges in covalent ligand discovery.

Key Responsibilities:
  • Design and evaluate novel assays and chemotypes to tackle challenges in covalent ligand discovery
  • Collaborate with cross-functional teams to develop and implement new research strategies
  • Conduct biochemical, biophysical, and cellular characterization of protein-ligand interactions
  • Develop and implement medium-to-high throughput compound screening strategies
Requirements:
  • PhD in Chemical Biology, Chemistry, Biochemistry, or Biological Science with at least 2 years of related postdoctoral and/or industry experience
  • Background in covalent ligand discovery with an emphasis in biophysics or cellular studies and a working knowledge of organic chemistry
  • Knowledge of concepts governing compound binding affinity and reactivity, kinetics, and selectivity
  • Ability to work collaboratively and thrive in a multitasking environment
  • Fluent English (spoken and written)
Why Novartis:

At Novartis, we are committed to reimagining medicine to improve and extend people's lives. Our purpose is to become the most valued and trusted medicines company in the world. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.



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