Biomarker Research Scientist

2 weeks ago


Watertown, Massachusetts, United States Acrivon Therapeutics Full time
Position Overview

Acrivon Therapeutics is a pioneering biopharmaceutical organization focused on the development of precision oncology therapies tailored to individual patient needs. Our innovative approach leverages the Acrivon Predictive Precision Proteomics (AP3) platform, which facilitates the identification of patients whose tumors are likely to respond to specific treatments based on a comprehensive analysis of tumor cell protein signaling networks.

The Biomarker Research Scientist will play a crucial role within the Biomarker Development Team, contributing to laboratory investigations aimed at biomarker discovery and translational research in oncology. This position involves both independent and collaborative work within a cross-functional team, providing opportunities to enhance understanding of drug mechanisms and resistance.

Key Responsibilities
  • Engage in the drug-specific biomarker discovery process, including selection and screening to develop assays for identifying cancer patients suitable for targeted therapies.
  • Participate in translational research initiatives to analyze clinical data and validate biomarker expression using archived and patient-derived cancer tissue samples, alongside in vitro and in vivo models.
  • Collaborate with a diverse team of researchers across various oncology disciplines and maintain strong partnerships with internal and external stakeholders.
  • Stay informed on scientific advancements by reviewing relevant literature and integrating new findings into ongoing projects.
  • Contribute to the preparation of scientific publications to disseminate research findings.
Qualifications
  • PhD in cell biology, cancer biology, or a related scientific field, with 1-2 years of relevant experience in either academia or industry.
  • Strong experimental foundation with a proven track record in hypothesis-driven translational research, including the design and execution of biomarker development experiments.
  • Experience in analyzing and interpreting biomarker data in both preclinical and clinical contexts, with knowledge of biomarker discovery processes.
  • Proficiency in microscopy techniques, including Brightfield and fluorescence, for assay development.
  • Demonstrated skills in developing and optimizing in vitro/ex vivo assays.
  • Excellent communication and interpersonal abilities, with a talent for effective collaboration in high-achieving team environments.
  • Ability to synthesize complex scientific concepts, formulate and test hypotheses, and troubleshoot challenges constructively.
  • A strong publication record in high-impact, peer-reviewed journals is highly desirable.
  • Capability to work independently and manage multiple projects in a dynamic environment.

Acrivon Therapeutics is committed to fostering an inclusive workplace and is proud to be an equal opportunity employer, ensuring equal access to employment opportunities for all individuals without regard to race, color, religion, sex, gender identity, national origin, age, disability, sexual orientation, or genetics.



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