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Senior Molecular Imaging Expert

2 months ago


Cambridge, Massachusetts, United States Novartis Group Companies Full time

Job Summary

We are seeking a highly skilled Senior Molecular Imaging Expert to join our Clinical Imaging & Analytics team at the Novartis BioMedical Research. As a key member of our Biomarker Development group, you will provide strategic leadership on the optimal use of imaging in drug development.

About the Role

The successful candidate will work closely with clinical trial teams to determine the role of imaging endpoints in new biological pathways across different therapeutic areas. You will have a wide view of molecules across various stages as they transition from research to early development and subsequently to Ph2-3 trials.

Key Responsibilities

  • Act as an internal expert in PET/SPECT and Molecular Imaging with a focus on clinical trials.
  • Partner with Oncology and General Medicine teams to develop and lead a "fit for purpose" imaging strategy and execute on it.
  • Implement Imaging in clinical trials to add critical insights on patient eligibility, efficacy, safety, and mechanism of action.
  • Collaborate and execute imaging readouts with internal operational support and external contract research organizations (CRO).
  • Ensure quality and timely execution of imaging trials to deliver critical drug development decisions.
  • Develop and manage a network of external experts and synthesize optimal inputs for specific protocols.
  • Collaborate with Research teams to develop and lead translational imaging studies.
  • Drive molecular imaging and ligand development from late pre-clinic to clinic.
  • Identify and/or develop novel imaging techniques and endpoints and implement them into clinical trials.

Requirements

  • PhD, MD, or MD/PhD with 3+ years of experience in PET/SPECT Imaging (academic or industry).
  • Technical knowledge in PET and SPECT for preclinical and clinical readouts.
  • Experience in clinical Radioligand/Radiopharmaceutical Therapy (RLT/RPT) is a plus.
  • Expertise in Radiochemistry and novel ligand development from bench to clinic is a plus.
  • Experience in regulatory submission, FIH, dosimetry, and receptor occupancy of molecular ligands is a plus.
  • Understanding of clinical trial design, statistics for endpoints, and clinical data flow is a plus.
  • Project management experience and working with imaging CROs; understanding of sites, budgets, and multisite trials is a plus.
  • Proactive, self-motivated, and independent working style.

Benefits and Rewards

We offer a competitive salary range of $118,400 - $177,600/year, as well as a comprehensive benefits package, including medical, financial, and paid time off benefits.

Commitment to Diversity and Inclusion

The Novartis Group of Companies is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.