Research Associate II/Senior Research Associate, Protein Engineering and Molecular Sciences
4 weeks ago
We are seeking a highly skilled Research Associate II/Senior Research Associate to join our Protein Engineering and Molecular Sciences Team at Repertoire Immune Medicines. The ideal candidate will have hands-on experience in analytical and biophysical QC of protein batches, including size exclusion HPLC, SDS-PAGE, DSF, ELISA, and/or Octet/SPR. The selected candidate will work at the bench to QC TCR bispecifics and MHC proteins, conduct stability/developability assessments to prioritize therapeutic leads, and develop robust assays for tech transfer to manufacturing partners.
Key Responsibilities- Perform analytical and biophysical QC of protein batches using techniques such as size exclusion HPLC, SDS-PAGE, DSF, ELISA, and/or Octet/SPR.
- Develop and document robust analytical assays for tech transfer to manufacturing partners.
- Conduct comparability, developability, and accelerated stability assessments of lead therapeutic molecules.
- Capture primary data, establish and maintain SOPs, and document work as required in Electronic Laboratory Notebook (ELN), maintaining up to date records.
- Present data routinely to the Protein Sciences group and other multidisciplinary groups.
- BS/MS in Biochemistry, Biology, Bioengineering, Immunology, or a similar field.
- 2+ years of academic or biotech/pharma laboratory experience.
- Experience with HPLC systems and with biochemical assays such as ELISA, SDS-PAGE, and DSF.
- Experience with Octet, SPR, or flow cytometry a plus.
- Strong organizational and communication skills along with excellent attention to details.
- Enjoys working in a collaborative, fast-paced, and quickly changing environment.
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Research Associate II
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Cambridge, Massachusetts, United States Skills Alliance Full timeJob SummaryWe are seeking a highly motivated and passionate research associate to support drug discovery projects. The successful candidate will have a solid understanding of protein biochemistry and molecular biology, with experience in structural biology being advantageous.Key Responsibilities:Develop and execute strategies to clone and express recombinant...
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Research Scientist
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