Associate Director/Director, Precision Oncology Research
3 days ago
We are seeking a highly motivated and experienced Associate Director/Director, Precision Oncology Research to join our team at Flagship Pioneering. As a key member of our research team, you will be responsible for leading the translational validation of discovery platform targets in cell-based and disease-relevant pharmacological models.
Key Responsibilities:- Design and implement high-quality in vitro and in vivo assays to evaluate the mechanisms of action of the target.
- Lead target validation activities, including target assessment, prioritization, and the development and execution of workplans.
- Coordinate with external research vendors to plan and execute animal studies, defining tissue and disease-specific target engagement levels, and establishing biomarker plans and translational PK/PD assessments.
- Provide strategic direction and oversight for concurrent research projects, collaborating with drug design, pharmacology, and translational research teams to advance candidate molecules through the drug discovery pipeline.
- Mentor and train junior scientists within the group as needed, ensuring the timely delivery of key team deliverables.
- Ph.D. in Cancer Biology, Immunology, or a related discipline with years of experience in a biotech or pharmaceutical company.
- Comprehensive knowledge and understanding of tumor intrinsic mechanisms (oncogenic drivers, cancer vulnerabilities) and target validation for drug discovery.
- Proven experience in screening and prioritizing targets derived from target identification efforts, leading target programs from identification to late drug discovery phases.
- Extensive hands-on experience in mammalian cell culture, including primary cells and tissue handling, as well as designing and executing tumor animal models, and conducting pharmacokinetic (PK) and pharmacodynamic (PD) analyses.
- Proven experience in directly supervising and mentoring scientists and research associates, and collaborating in cross-functional/matrix environments.
Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
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Cambridge, Massachusetts, United States Flagship Ventures Full timeJob Title: Associate Director/Director, Precision OncologyFlagship Pioneering's venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. We are seeking a talented and highly motivated Associate Director/Director Oncology to play...
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Senior Oncology Research Director
2 weeks ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeJob Title: Associate Director/Director, Precision OncologyFlagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability.About the Role:We are seeking a highly motivated and experienced Associate Director/Director, Precision...
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Director, Evaluative Research
3 weeks ago
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Cambridge, Massachusetts, United States BioSpace, Inc. Full timeJob DetailsThe Role:Moderna is seeking a Clinical Biomarker leader to drive biomarker assay plans across clinical stage oncology programs. This position reports to Moderna's Director of Clinical Biomarkers. The Associate Director will work collaboratively across several clinical teams (internal, external CROs) to ensure biomarker assay development strategy,...
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Director of Evaluative Research
3 weeks ago
Cambridge, Massachusetts, United States Forrester Research Full timeAbout This RoleForrester Research is seeking a seasoned professional to lead the operations of our evaluative research product portfolio. This role involves overseeing the standardization of the product portfolio, working with research teams to execute on evaluative research projects, communicating the value of the product set to stakeholders, and optimizing...
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Associate Director Clinical Science
3 weeks ago
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Associate Director Clinical Science
3 weeks ago
Cambridge, Massachusetts, United States FogPharma Full timeAbout the RoleFogPharma is a pioneering biopharmaceutical company revolutionizing the discovery and development of Helicon therapeutics. We are seeking an exceptional Associate Director Clinical Science to join our Clinical Development team.Key ResponsibilitiesIntegrate scientific knowledge and operational expertise to ensure translation of clinical research...
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Principal Research Scientist
3 weeks ago
Cambridge, Massachusetts, United States CULLINAN ONCOLOGY LLC Full timeAbout Cullinan Oncology LLCCullinan Oncology LLC is a biopharmaceutical company dedicated to creating innovative treatments for patients. Our mission is to develop transformative therapeutics that improve patient outcomes.Job SummaryWe are seeking a highly skilled Principal Scientist/Associate Director to oversee and support early-stage drug development...
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Director, Precision Medicine Strategy Lead
2 weeks ago
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Medical Director
3 weeks ago
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Cambridge, Massachusetts, United States AAPC Full timeJob SummaryEisai is seeking an experienced Associate Director/Director, Medical Science Liaison to lead our East Region, GI/GU, Oncology team. As a key member of our Medical Affairs team, you will be responsible for providing strategic and tactical leadership to our Medical Science Liaisons, working collaboratively with cross-functional teams to support...
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Cambridge, Massachusetts, United States Harvard University Full timeJob SummaryWe are seeking a highly skilled Associate Director of Finance and Research Administration to join our team at Harvard University. The successful candidate will be responsible for managing all grants administration and financial activities for the Department of Psychology.The Associate Director of Finance and Research Administration will oversee...
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Medical Director
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Associate Director Biostatistics
2 weeks ago
Cambridge, Massachusetts, United States Relay Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Associate Director, Biostatistics to join our team at Relay Therapeutics. As a key member of our clinical development team, you will be responsible for leading the statistical aspects of our clinical studies, ensuring the integrity and quality of our data, and collaborating with cross-functional teams to drive...
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Cambridge, Massachusetts, United States GSK Full timeJob Title: Associate Director, Epidemiology Bacterial VaccinesGSK is seeking an experienced Associate Director to lead our Epidemiology team in the development of bacterial vaccines. As a key member of our Global Epidemiology, Vaccines team, you will drive epidemiology strategy and studies across the spectrum of vaccine development.Key...
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Associate Director, New Product Planning
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Cambridge, Massachusetts, United States FogPharma Full timeAbout the RoleFogPharma is a pioneering biopharmaceutical company revolutionizing the discovery and development of Helicon therapeutics, peptides capable of efficient cell entry and modulation of protein-protein and protein-DNA interactions.We are seeking an experienced Associate Director, New Product Planning to join our team and drive key business...
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Medical Director
11 hours ago
Cambridge, Massachusetts, United States AL Solutions Full timeMedical Director Opportunity in Immuno-OncologyWe are working with an innovative company in the field of immuno-oncology to find a Medical Director to lead their clinical development and medical strategy. This is a unique chance to work with a leading-edge company and contribute to advancing cancer treatments.The Role:As the Medical Director, you will...
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Cambridge, Massachusetts, United States Moderna Therapeutics Full timeAbout the RoleModerna Therapeutics is seeking a highly skilled and strategic Director of Shared Antigen Cancer Vaccines Research to join our Cancer Vaccines Research team, focusing on early pipeline programs.Key ResponsibilitiesLead the early discovery and preclinical validation of shared antigen cancer vaccine candidates, overseeing the translation of...
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Associate Director Clinical Science
2 weeks ago
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Cambridge, Massachusetts, United States Moderna Therapeutics Full timeAbout the RoleWe are seeking a highly experienced and accomplished Director of Translational Research to join our Cancer Vaccine Research team at Moderna Therapeutics. As a key member of our research organization, you will be responsible for leading a team of scientists and researchers in the design, implementation, and execution of translational research...
