Research Associate in Cardiovascular Science

2 weeks ago


Columbus, Ohio, United States American Society Of Gene & Cell Therapy Full time
Position Overview
A full-time research associate role is currently open in the laboratory of Dr. Deqiang Li, situated within the Center for Cardiovascular Research at the American Society Of Gene & Cell Therapy. This position is funded by a significant NIH R01 grant.

Research Focus
The primary aim of our research is to elucidate the underlying mechanisms of cardiovascular development, disease, and regeneration. We are particularly focused on discovering novel signaling pathways that influence myocardial development and regulate cardiomyocyte differentiation and maturation through both in vitro and in vivo methodologies.

Role Responsibilities
Utilizing advanced cell and mouse model systems, including induced pluripotent stem cells (iPSCs) and conditional gene knockout techniques, the successful candidate will engage in a variety of research projects. Our laboratory employs cutting-edge techniques such as:
1. CRISPR/Cas9 Genome Editing
2. AAV
3. Single-cell RNA sequencing and ChIP sequencing
4. Confocal microscopy
5. Multicolor flow cytometry and sorting
6. Surgical models
7. Ultrasonic and telemetric assessments of cardiovascular function in murine models.

Candidate Requirements
Applicants must possess a PhD, MD, or an equivalent qualification, along with demonstrated expertise in molecular biology, mouse genetics, or the development of cardiac surgical models in mice. We are in search of driven and self-motivated candidates who exhibit a strong work ethic and a profound interest in cardiovascular development and regeneration.

Preferred Qualifications
Candidates with a background in developmental biology, particularly those experienced in utilizing mouse models, iPSCs, or the creation of cardiac surgical mouse models, are highly encouraged to apply.

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