Principal Scientist-antibody Discovery

3 weeks ago


San Diego, United States Bristol-Myers Squibb Full time

**Working with Us**
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

As part of the Discovery Biotherapeutics efforts at BMS, the Functional Assays team plays a key role in discovering and characterizing a first
- and best

**Responsibilities**
- Manage multiple antibody/binder discovery processes - develop fit-for-purpose primary screening assay and provide characterization support for lead molecules.
- Enable and maintain our biologics drug discovery operations: represent departmental function on project teams. Identify and manage research collaborations/CROs, collaborate with other stakeholders across Discovery Biotherapeutics sites.

**Basic Qualifications**

Bachelor's Degree with 8+ years of academic or industry experience

Or

Master's Degree with 6+ years of academic or industry experience

Or

PhD with 4+ years of academic or industry experience

**Preferred Qualifications**
- PhD with 4+ years of industry experience
- Significant experience in assay validation, antibody primary screening, and downstream MOA profiling
- In-depth knowledge and hands-on experience in various techniques for protein and antibody characterization, including BLI or SPR, flow cytometry, and high content imaging
- Data processing experience with workflows using Genedata or other equivalent data management system
- Hands-on experience working with neurodegenerative, immunosciences, or oncology biologics

**For California Sites**:
**Uniquely Interesting Work, Life-changing Careers**

**On-site Protocol**

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.



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