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Principal Scientist

2 months ago


San Diego, United States Lilly Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly’s Biotechnology Discovery Research (BioTDR) organization has a track record for delivering novel biotherapeutic medicines to advance into clinical research in key areas of unmet medical need including diabetes, oncology, immunology, neuroscience, and others.

**Responsibilities**
- Support discovery and engineering efforts using emerging technologies for antibody display including affinity maturation
- Execute antibody discovery and engineering strategies for lead identification and optimization
- Run in-house processes for library construction for discovery, and perform library screening and selections
- Independently perform complex experiments with attention to quality, detail and documentation
- Interpret data, troubleshoot experiments and present work at internal meetings

**Basic Qualification**
- Bachelor's degree in Biology or related field.
- 5+ years of experience in Antibody discovery and/or Engineering

**Preferred Requirements/Skills**
- Knowledge and hands-on experience in library construction and/or screening
- Experience with yeast, phage, RNA display and/or other discovery and molecular evolution technologies
- Experience in FACS technology, applied to screening and selection activities
- Prior work with antibody libraries, affinity maturation and antibody/protein engineering would be a plus

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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