Principal Scientist-antibody Discovery

2 weeks ago


San Diego, California, United States Bristol-Myers Squibb Full time

Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department.

From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity.

Take your career farther than you thought possible.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.


The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.

We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential.

By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

As part of the Discovery Biotherapeutics efforts at BMS, the Functional Assays team plays a key role in discovering and characterizing a first
- and best

Responsibilities

  • Manage multiple antibody/binder discovery processes develop fitforpurpose primary screening assay and provide characterization support for lead molecules.
  • Enable and maintain our biologics drug discovery operations: represent departmental function on project teams. Identify and manage research collaborations/CROs, collaborate with other stakeholders across Discovery Biotherapeutics sites.

Basic Qualifications
Bachelor's Degree with 8+ years of academic or industry experience

Or

Master's Degree with 6+ years of academic or industry experience

Or

PhD with 4+ years of academic or industry experience

Preferred Qualifications

  • PhD with 4+ years of industry experience
  • Significant experience in assay validation, antibody primary screening, and downstream MOA profiling
  • Indepth knowledge and handson experience in various techniques for protein and antibody characterization, including BLI or SPR, flow cytometry, and high content imaging
  • Data processing experience with workflows using Genedata or other equivalent data management system
  • Handson experience working with neurodegenerative, immunosciences, or oncology biologics

For California Sites:

Uniquely Interesting Work, Life-changing Careers

On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs.

The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility.

For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.

For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.

As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

  • San Diego, California, United States Johnson & Johnson Full time

    Job DescriptionJohnson & Johnson Innovative Medicine is seeking a Scientist, Discovery Data Science to join the team in advancing Artificial Intelligence/Machine Learning (AI/ML) for Drug Discovery. This role is based at the R&D site in San Diego, CA (La Jolla area). At Johnson & Johnson, our mission is focused on transforming healthcare. We are dedicated...


  • San Diego, California, United States Johnson and Johnson Full time

    Senior Scientist, Discovery Data Science - Johnson & Johnson Innovative MedicineJohnson & Johnson is currently seeking a talented Senior Scientist to join their Innovative Medicine team. As a Senior Scientist, you will play a crucial role in advancing Artificial Intelligence/Machine Learning (AI/ML) for Drug Discovery. This position is based in La Jolla, CA,...

  • Principal Scientist

    1 month ago


    San Diego, California, United States Bristol-Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life–changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Principal Scientist

    4 weeks ago


    San Diego, California, United States Bristol-Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life–changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Principal Scientist

    4 weeks ago


    San Diego, California, United States Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Principal Scientist

    1 month ago


    San Diego, California, United States Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Principal Scientist

    1 month ago


    San Diego, California, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • San Francisco, California, United States Prellis Bio Full time

    Prellis Biologics employs proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro antibody libraries, camelid antibody libraries, in vitro human immunogenicity screening, and in vitro human tumor/lymph node cocultures for therapeutic screening. Prellis' ability to print and culture healthy human tissue provides it...


  • San Diego, California, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • San Diego, California, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • San Diego, California, United States Johnson & Johnson Full time

    Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, is recruiting for a Principal Scientist, Computer-Aided Drug Design (CADD, Computational Chemistry) located in San Diego, CA (La Jolla area).At the Janssen Pharmaceutical Companies of Johnson & Johnson, we work to create a world without disease. Transforming lives...


  • San Diego, California, United States University of California, San Diego Full time

    Assistant, Associate, or Full Project Scientist in Molecular BiologyPOSITION DESCRIPTIONThe Department of Molecular Biology in the School of Biological Sciences is conducting an open search for Project Scientists (non-tenured, Assistant, Associate or Full level). At UC San Diego, Project Scientists are academic researchers who are expected to make...


  • San Diego, California, United States University of California, San Diego Full time

    Assistant, Associate, or Full Project Scientist in Molecular BiologyPOSITION DESCRIPTIONThe Department of Molecular Biology in the School of Biological Sciences is conducting an open search for Project Scientists (non-tenured, Assistant, Associate or Full level). At UC San Diego, Project Scientists are academic researchers who are expected to make...


  • San Diego, California, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • San Diego, California, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products...


  • San Diego, California, United States Integrated Resources Full time

    This position offers the opportunity to be part of company discovery teams focused on creating Client, highly specific and selective drugs for genetically identified targets. The Protein Scientist will support the internal and external discovery research efforts across multiple projects and project teams. This is an extremely important role where the right...


  • San Diego, California, United States Talentry LLC Full time

    Job DescriptionPrincipal Scientist, Mammalian Cell Culture (CHO) San Diego, CA Hybrid Direct Hire. 140k-175k. Talentry is looking for a Principal Scientist who has proven mammalian cell culture expertise (CHO). This scientist will focus on cell culture process development for upstream processes with respect to mammalian cells, including CHO cells.The right...

  • Sr. Scientist I

    1 month ago


    San Diego, California, United States AnaptysBio, Inc. Full time

    Job TypeFull-timePosition SummaryThis position is involved in the initiation, strategic design, implementation, and execution of antibody-based drug discovery projects in autoimmunity and inflammation. This includes applying advanced scientific principles and concepts in immunology and inflammation to creatively and effectively solve difficult problems and...

  • Sr. Scientist I

    4 weeks ago


    San Diego, California, United States AnaptysBio, Inc. Full time

    Job TypeFull-timePosition SummaryThis position is involved in the initiation, strategic design, implementation, and execution of antibody-based drug discovery projects in autoimmunity and inflammation. This includes applying advanced scientific principles and concepts in immunology and inflammation to creatively and effectively solve difficult problems and...