Research Associate, Antibody Discovery
2 months ago
Overview
AlivaMab Biologics is seeking an outstanding individual with a broad range of skills to support the successful discovery of fully human antibody drug candidates from the AlivaMab Mouse platform. The successful candidate will be a highly motivated team player and able to multitask in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs.
The annualized anticipated base annual salary for this Research Associate position ranges from $52,800 to $73,000. Additionally, this position offers an annual bonus, equity, and other benefits. Please note that individual total compensation for this position will be determined at the Company's sole discretion and may vary based on several factors, including but not limited to: location, skill level, years and depth of relevant experience, and education.
Other benefits offered include a 401K retirement savings plan, paid time off (vacation/personal days, holidays, and sick time), long- and short-term disability, health benefits (medical, prescription drug, dental and vision insurance), gym access, and more.
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics, and developability, with expanding capabilities for engineering alternative formats, including multispecifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
Responsibilities
Responsibilities
* Maintenance of mammalian cell lines for cell-based assays for multiple projects
* Mouse immunizations, sera titer check, tissue collection
* Antibody screening utilizing ELISA, flow cytometry, and cell-based functional assays.
* Reagent preparation and keeping inventory up to date.
* Take on the role of an independent and creative researcher who demonstrates initiative in experimental design and execution, including troubleshooting.
* Work closely with other team members and leaders supporting multiple drug discovery projects.
* Effectively present and communicate concepts and results, both orally and in writing, to the team.
Qualifications
Qualifications
Key Skills and Requirements:
* BS or MS in Immunology, cell biology, or related discipline with 0-3 years of relevant industrial or academic experience.
* Aseptic tissue culture experience is a requirement for the position (in either industry or academic settings.) Demonstrated technical expertise in mammalian tissue culture of cancer cell lines and hybridomas is preferred.
* Handling small animals including immunization, blood drawing, and harvesting tissue is highly desired.
* Ability to efficiently work both independently and in a team-based environment on challenging drug discovery projects utilizing high-throughput cell culture and antibody screening techniques.
* Proficiency in Microsoft Office (Word, Excel and PowerPoint) and GraphPad Prism. Experience with Benchling ELN/LIMS is a plus.
* The right candidate for excelling in this position will be self-motivated, display strong attention to detail, and have a desire to learn and develop new skills and techniques for antibody drug discovery.
* Experience and /or knowledge desired but not required for this position:
* Antibody screening with ELISA, ELISA, and/or cell-based assays
* Experience with stable cell line generation, FACS sorting, and/or experimental design of cell-based assays
* Local candidate preferred. No relocation assistance is offered for this position.
About AlivaMab Biologics
AlivaMab Biologics (AMB) sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
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