AD / Sr. Principal Scientist - CADD

2 months ago


San Diego, California, United States Novartis Full time

The Computer-Aided Drug Discovery (CADD) group in San Diego is seeking an AD/Senior Principal Scientist to join our talented and innovative drug discovery team.Develop, improve and implement efficient computational workflows that can be distributed to our global CADD teamInitiate drug discovery efforts by proposing novel targets / modalities, evaluating target druggability and executing in silico hit generation, triage and expansion methodologiesKeep abreast of scientific developments and interact with internal and external scientists to integrate novel insights into computational approaches for drug discoveryPhD in computational chemistry, computational biology, computational chemical biology, or related field7+ years of pharmaceutical industry experience applying computational methods to drug discovery and small molecule design as a member of therapeutic project teamsExpert proficiency in one or more commercial drug discovery platform such as ICM, Schrödinger, CCG and/or OpenEyeExtensive expertise in structure-based drug discovery, medicinal chemistry principles, cheminformatics, ADME and ML/AI


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