AD / Sr. Principal Scientist - CADD

2 months ago


San Diego, United States Novartis Full time
  • The Computer-Aided Drug Discovery (CADD) group in San Diego is seeking an AD/Senior Principal Scientist to join our talented and innovative drug discovery team.
  • Develop, improve and implement efficient computational workflows that can be distributed to our global CADD team
  • Initiate drug discovery efforts by proposing novel targets / modalities, evaluating target druggability and executing in silico hit generation, triage and expansion methodologies
  • Keep abreast of scientific developments and interact with internal and external scientists to integrate novel insights into computational approaches for drug discovery
  • PhD in computational chemistry, computational biology, computational chemical biology, or related field
  • 7+ years of pharmaceutical industry experience applying computational methods to drug discovery and small molecule design as a member of therapeutic project teams
  • Expert proficiency in one or more commercial drug discovery platform such as ICM, Schrödinger, CCG and/or OpenEye
  • Extensive expertise in structure-based drug discovery, medicinal chemistry principles, cheminformatics, ADME and ML/AI


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