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Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
This is an exciting opportunity to advance our precision medicine efforts by developing tissue-based assays to support patient selection strategies. Applicants chosen for this position will directly interact with diverse clinical and scientific colleagues to advance cutting-edge clinical trials programs. Projects include development of assays using immunohistochemistry, multiplex staining/imaging, in situ nucleic acid hybridization, and digital pathology. The scientist will be directly responsible for the design, development, execution, and analysis of translational tissue-based biomarker assays to interrogate target prevalence, target engagement, mechanisms of action, pharmacokinetics, pharmacodynamics, and prediction of treatment response. The position entails working on projects independently and in multi-disciplinary teams consisting of pathologists, lab scientists, data scientists and clinical biomarker scientists. The IHC scientist will develop tissue-based assays for internal or external use with accountability for assays transferred to partner labs and contract research organizations (CROs). The scientist will also be responsible for working with digital pathology colleagues to build and assess image analysis algorithms and workflows.
The ideal candidate will have technical experience in IHC assay development and techniques and a basic knowledge of histology/morphology/pathology interpretation relevant to assay development. The scientist must show strong communication and organizational skills, the ability to work collaboratively with other team members, adaptability to regulated work environments and the flexibility to accommodate changing business needs.
CORE JOB FUNCTION(S):
* The scientist will assist or independently coordinate and perform all aspects of assay development spanning project intake, planning, development, and execution of assays including (but not limited to) chromogenic immunohistochemistry (IHC), in-situ nucleic acid hybridization, multiplexed immunofluorescence (mIF) and digital pathology
* Participate in developing assay workflow strategies (feasibility, verification, and validation), with appropriate knowledge and use of controls
* Responsible for planning, coordination, and execution of assays transferred to vendor sites with communication/problem solving with vendor
* Maintain technical proficiency across several IHC, mIF, histology/tissue processing and digital scanner technologies
* Provide concise yet thorough project overviews and timelines to leadership and stakeholders
* Contribute to design control processes and CAP/CLIA lab work, documentation, and planning (when needed)
* Coordinate, execute and document clinical trial sample and commercial sample assay development and deployment within BMS labs
* Develop and learn digital image analysis for assay quality assessment and analysis of slides (H&E, IHC and mIF)
* Maintain workplace and lab compliant processes and documentation
* Familiar/keeps current with literature relevant to work
* Excellent communication and interpersonal skills and can effectively communicate via email, meetings, and reports
* Participates in the development of relevant documentation (e.g., patent applications, publications, SOPs, regulatory submissions, protocols, etc.)
* Participates in continuous improvement or development of new/improved work practices
* Requires significant level of developed knowledge of the principles and concepts of a discipline
* Designs and executes experiments based on protocols
* Works within established procedures and in loosely defined problem-solving situations on more occasions
* Actively participates in troubleshooting of routine problems and initiatives
* Works under minimal supervision for both routine and non-routine activities
* Makes decisions that impact own work and other group/team members
* Participates on program/project teams, as needed
* Shares knowledge with other colleagues to accomplish team goals
* This is a lab-based position requiring on-site work >80% of the time (averaged across 2 weeks)
Basic Qualifications:
* Bachelor's Degree
* 4+ years of academic and / or industry experience
Or
* Master's Degree
* 2+ years of academic and / or industry experience
Preferred Qualifications:
* Research experience in the field of cancer biology and immunology
* Experience in the design and development of IHC and mIF assays using various technology platforms including but not limited to the Leica Bond RX and Ventana Benchmark Ultra
* Experience using slide scanner technologies including, but not limited to, Zeiss Axioscanner, Leica GT450, Leica AT2 and Akoya Polaris
* Experience with basic lab practices including, but not limited to, ordering, inventory, documentation, budgeting, and electronic notebook
* Experience performing basic laboratory work including maintenance of lab equipment, automated IHC equipment and histology equipment
* Familiarity with assay qualification/validation guidelines and guidance (FDA, CAP, CLIA, NYSDOH, global regulatory requirements for assay development).
* Basic understanding of IVD quality system standards (21 CFR part 820, ISO13485)
* Knowledge of clinical sample handling, analysis and regulatory and quality frameworks and guidance in the lab and at vendors (such as GCP, CLIA, CAP, and NYDOH)
* Ability to summarize and interpret scientific data in a clear, concise, and accurate manner
* Ability to clearly communicate well with peers and supervisors
* Exceptional organizational skills and meticulous attention to detail in managing in-lab tasks, personnel, and experimental protocols
* Strong problem-solving skills and understanding of relevant scientific principles
* Mindset focused on continuous improvement, actively seeking opportunities to enhance lab efficiency and safety
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
