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Associate Scientist I, Next Generation Sequencing

2 months ago


Cambridge, United States Editas Medicine Full time
Job DescriptionJob Description

At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

Together, we are leading the way towards a healthier and more equitable future.

Position Summary

The Next Generation Sequencing (NGS) team at Editas Medicine is seeking a motivated Associate Scientist I to help support the needs of a new class of therapies based on CRISPR-Cas gene editing. In this role, the candidate will use their experience in NGS technologies (library prep, quality control, sequencing hardware) to drive the successful translation of this technology into the clinic. They will assist with running existing Illumina and Oxford Nanopore processes as well as help develop new protocols and transition assays into production, as needed. Experience with automated DNA library prep, amplicon sequencing (target specific primer design, multiplex rhAmpSeq primer design for off target verification), and Oxford Nanopore sequencing (DNA, RNA and plasmid libraries) is desired. The position requires working effectively in a multi-disciplinary team, excellent written and verbal communication skills, and a capacity for creativity and innovation to achieve corporate objectives.

Requirements

  • B.S./M.S. in biology or related field with 2-5 years of relevant experience.
  • Experience with Illumina and Oxford Nanopore library construction, NGS primer design, and lab automation systems is highly desirable, as is programming automation.
  • Experience operating an Illumina MiSeq and Oxford Nanopore GridIon and interpreting data quality.
  • Experience transitioning protocols from R&D to production, including protocol development, optimization, scale-up, and process documentation (Benchling eLN, workflow diagrams), is desirable.
  • The ability to work in a team-oriented, timeline-focused, dynamic environment.
  • Excellent troubleshooting skills.
  • Excellent verbal and written communication skills.

Benefits

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.

Fostering Belonging. Fueling Innovation. Transforming Lives.