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Laboratory Technician

2 months ago


Rockville, United States Axle Full time
Job DescriptionJob Description

(ID: 2024-5942)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Match
  • Tuition reimbursement and professional development opportunities
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Overview
Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Laboratory Technician to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), TB Imaging Program (TBIP).


Technical Requirements:

  • Perform a broad range of procedures and tasks related to evaluating vaccine efficacy in a primate model of Mycobacterium tuberculosis (TB).
  • Isolate immune cells from a variety of animal blood and tissues under BSL2 and BSL3 lab conditions for downstream applications.
  • Perform a broad range of immunological assays related to the in vitro and in vivo evaluation of experimental TB vaccines: flow cytometry/cell sorting, Luminex/ELISA, bulk and single cell RNA isolation for sequence analysis.
  • Perform (BSL3) assays that relate to quantifying TB burdens from animal tissues culturing) and assessing anti-mycobacterial activity ex vivo following vaccination (ie, in vitro growth assays).
  • Conduct research independently including designing and executing experiments, writing animal protocols, data analysis and presentation, and preparation of data for publication.
  • Independently work on generation RNA sequencing data for immunological profiling.
  • Interact with scientists from our lab and other laboratories and institutions to implement 'best practice' data analysis pipelines related to transcriptional, epigenetic, and immunological analysis of immune samples after immunization.
  • Interact with students, post-doctoral fellows and non-doctoral research technicians on experimental design and laboratory-based methodologies.
  • Maintain detailed records of experiments and results and clearly communicate data to others in using reports and data, and for publication.
  • May be required to perform duties related to TB vaccine studies at an off-site location (Bioqual Inc., 2501 Research Blvd, Rockville, MD 20850) and maintain compliance with all training requirements of this non-NIH facility.
  • Responsible for laboratory upkeep and routine maintenance of equipment

Specific Qualifications:

  • Masters degree in related field is required.
  • Minimum of two (2) years of work experience in a laboratory setting is required.
  • Demonstrates knowledge of maintaining accurate and detailed records.
  • Proficient computer skills with spreadsheets and other software to record data.
  • Effective and clear communication skills and the ability to work in a high stress environment.
  • Must be able to pass extensive background check and Public Trust 5 clearance.
  • Willing to work flexible hours, weekend work possible.
  • Ability to work in a BSL-3 high containment environment is required.
  • Ability to work in a team under oversight in ABSL-3 laboratory environments following SOPs.
  • Ability to work in an Animal BSL-3 high containment environment is required.
  • In-person work in the BSL-3 laboratory and in ABSL-3 laboratory with NHPs, rabbits, and mice, required.

The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

Disclaimer:The above description is meant to illustrate the general nature of work and level of effort being performed by individual's assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.