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Senior Scientist

4 months ago

Andover, United States Insight Global Full time

Must-Haves:

  • Bachelor's Degree in related field
  • 3+ years of experience with mRNA drug substance process (such as in-vitro transcription reactions), Enzyme based process, and purification of biomolecules (such as Enzymatic reactions, AKTA Chromatography, UF/DF, Column Chromatography)
  • Purification process development and troubleshooting experience

Plusses:

  • Master's Degree
  • Familiarity with mRNA Lipid nano particle formulation and Final Drug Product (FDP) processes

Day to Day:

We are looking for 3 Downstream Scientists to join the Manufacturing Sciences and Technology (MSAT) organization at a large pharmaceutical client based out of Andover, MA. This MSAT downstream purification team supports downstream development purification and optimization, mRNA drug substance process activities, and providing support to routine manufacturing operations.

This person will be expected to develop and qualify purification techniques, ensure the proper and timely execution of purification processing, and perform scale-down purifications of biologics using precipitation, depth filtration, ultrafiltration, and chromatography. We are looking for someone with experience in techniques such as mRNA Drug Substance process, UF/DF, Column Chromatograph, and ideally familiar with standard downstream equipment, e.g. AKTAs.