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Senior Upstream Scientist

2 months ago

Andover, United States Insight Global Full time

Must Haves:

  • Bachelor's Degree in related field
  • 5+ years of bioprocessing experience – supporting manufacturing investigations
  • Lab based or Mammalian cell culture background
  • Chemistry or biology background is fine
  • Proficient in cell culture aseptic technique
  • Cell culture Bioreactor experience
  • Enjoys manipulating data
  • Cedex cell counter, Nova Flex2 nutrient analyzer, Blood Gas Analyzer

Pluses:

  • Master's Degree
  • Experience in supporting scale-up and technology transfer to pilot or commercial scale facilities
  • Experience in benchtop bioreactor operation and associated analytical tools – take samples to be analyzed, concentration of cells
  • Familiar with control and data acquisition systems
  • Experience with processing and interpreting large data sets
  • Knowledge of all aspects of cell culture/fermentations

Day to Day:

We are looking for a Senior Scientist to join the Manufacturing Sciences and Technology (MSAT) organization at a large pharmaceutical client based out of Andover, MA. This upstream cell culture and fermentation team supports late stage development and commercial biopharmaceuticals and vaccines, and responsible for process troubleshooting, process improvements, and second generation process development. This person will be expected to plan and execute well-designed lab experiments in cell culture and/or fermentation with pre-defined goals. This includes basic analytics, data acquisition and interpretation, user-level maintenance of the relevant equipment and documentation of work.

Responsibilities

  • Plan and execute upstream process experiments at benchtop scales
  • Operate and maintain benchtop bioreactors and associated analytic tools
  • Understand and adjust control and data acquisition systems
  • Document results and present them to internal teams
  • Assist in manufacturing investigations and process troubleshooting