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Director / Senior Director, Medicinal Chemistry
2 months ago
IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics.We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality – which represents an emerging class of precision medicine targets.It has established strategic collaborations with GSK, Amgen, Pfizer and Gilead supporting certain clinical and preclinical pipeline programs.Ph. D. in synthetic organic chemistry with 10+ to 15+ years pharmaceutical medicinal chemistry industrial experienceExpert understanding of medicinal chemistry concepts along with strong working knowledge of protein-ligand interactions, conformational and structural analysis to enable creative solutions to drug discovery issues.Exceptional knowledge of ADME, physicochemical, biochemical and pharmacological principles as applied to drug discoveryExperienced in partnering closely with other functional areas including: computational chemistry, DMPK, in vivo pharmacology, CMC, etc.Significant operational experience in one of the following disciplines: Analytical Chemistry, Computer Aided Drug Design, Structural Biology, Formulation Sciences, in vitro and/or in vivo ADME
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Medicinal Chemistry Research Specialist
5 days ago
South San Francisco, California, United States Septerna Inc. Full timePOSITION OVERVIEWWe are looking for a skilled medicinal chemist to enhance our chemistry initiatives for various drug discovery projects, collaborating within a multidisciplinary team. Your responsibilities will include the design of novel compounds, conducting synthesis in our in-house laboratories, partnering with Contract Research Organizations (CROs),...
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Senior Scientist, Medicinal Chemistry
5 days ago
San Diego, California, United States Belharra Therapeutics, Inc. Full timeABOUT US Belharra Therapeutics is a pioneering small molecule discovery firm established by leaders in chemical biology. By leveraging our unique chemoproteomics platform alongside cutting-edge biology and medicinal chemistry, we are innovating protein function modulation in unprecedented ways to enhance drug discovery. Our mission is to provide...
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Director/Senior Director, CMC Analytical
2 months ago
South San Francisco, California, United States Annexon, Inc. Full timeWork LocationCorporate Headquarters (South San Francisco, CA) Onsite – HybridPosition SummaryThe Director/Senior Director – CMC Analytical incumbent is responsible for working closely with the SVP, CMC Research in leading and maintaining QA Manufacturing Operations. The Director/Senior Director – CMC Analytical will Lead preclinical to clinical...
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San Francisco, California, United States Nurix Therapeutics Full timeCompanyNurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries,...
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Senior Director of Clinical Quality Assurance
1 month ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. Alumis is hiring a Clinical Quality Assurance...
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San Francisco, California, United States Nurix Therapeutics Full timeCompanyNurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries,...
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Director, Process Development
1 month ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. We are seeking an experienced highly motivated...
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South San Francisco, California, United States Surf Search Full timeDirector/Senior Director, Regulatory Medical Writing (Remote).Position Overview: The position, reporting to the Sr. Director, Head of Global Regulatory Portfolio Management, with a dotted line reporting to the Interim Head of Medical Writing, will be the medical writing lead for clinical regulatory documents. A successful medical writer will be able to write...
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Associate Director/Director
2 months ago
South San Francisco, California, United States Annexon, Inc. Full timeWork LocationCorporate Headquarters (South San Francisco, CA) Position SummaryThis position reports into the Vice President / Executive Director of Global Clinical Operations. The Associate Director/Director - Clinical Operations (Ophthalmology) will contribute to the development and implementation of clinical studies. Responsibilities include providing...
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Scientist I/II, Medicinal Chemistry
2 months ago
San Francisco, California, United States Nurix Therapeutics Full timeAbout the PositionWe are seeking a talented and highly motivated individual with a strong background in synthetic organic chemistry to join our medicinal chemistry group in the pursuit of novel small molecules to treat patients with unmet medical needs. Working closely with our computational chemistry and modeling group, the successful candidate will design...
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Head of Peptide Chemistry Research
4 days ago
San Francisco, California, United States Johnson Service Group Full timePosition Overview:Johnson Service Group is seeking a highly qualified individual for the role of Director of Peptide Chemistry R&D. This pivotal position will be based in a dynamic environment focused on advancing peptide research. The Director will be responsible for steering the Peptide Research Department, managing peptide design, synthesis, and various...
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Senior Medical Director, Dermatology
3 months ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. We are seeking an experienced Senior Medical...
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Advisor - Computational Chemistry
2 months ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
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Associate Director, CMC Analytical Development
2 months ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.The small molecule CMC team is seeking a highly...
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Senior Director's Assistant
2 months ago
San Francisco, California, United States Pacific Gas and Electric Company Full timeRequisition ID # Job Category: Administrative / Clerical Job Level: Individual ContributorBusiness Unit: Operations - OtherWork Type: HybridJob Location: Auburn; Alameda; Alta; American Canyon; Angels Camp; Antioch; Auberry; Avenal; Avila Beach; Bakersfield; Balch Camp; Bear Valley; Belden; Bellota; Belmont; Benicia; Berkeley; Brentwood; Brisbane; Buellton;...
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Lead Scientist
4 days ago
San Diego, California, United States Flexi Finance Full timePrincipal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewAbout UsAt Flexi Finance, we are committed to delivering innovative solutions that have a meaningful impact on the financial industry. Our work environment is designed to foster creativity and collaboration, allowing our employees to thrive in their careers while...
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Lead Scientist
4 days ago
San Diego, California, United States Flexi Finance Full timePrincipal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewWorking with UsAt Flexi Finance, we redefine the conventional work experience. Here, you will engage in fascinating and impactful projects that contribute to the advancement of financial solutions. Collaborating with talented teams, you will have the opportunity...
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Medical Director
5 hours ago
San Francisco, California, United States Stacy Medical Center Full timeJob SummaryStacey Medical Center is seeking a highly skilled Medical Director to lead our occupational medicine team. As a key member of our staff, you will be responsible for providing high-quality medical care to workers who have sustained injuries or illnesses on the job.ResponsibilitiesPractice occupational medicine and conduct patient...
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Associate Director, Clinical Operations
2 months ago
South San Francisco, California, United States Alumis Inc. Full timeAlumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. The Associate Director of Clinical Operations...
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South San Francisco, California, United States Annexon, Inc. Full timeWork LocationCorporate Headquarters (South San Francisco, CA) – HybridPosition SummaryThis role provides global regulatory leadership and direction to support the development, registration, and life-cycle management of innovative programs within the Annexon portfolio. Responsibilities include developing regulatory strategies and detailed plans to meet...