Director / Senior Director, Medicinal Chemistry

2 months ago


South San Francisco, California, United States IDEAYA Biosciences Full time

IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics.We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality – which represents an emerging class of precision medicine targets.It has established strategic collaborations with GSK, Amgen, Pfizer and Gilead supporting certain clinical and preclinical pipeline programs.Ph. D. in synthetic organic chemistry with 10+ to 15+ years pharmaceutical medicinal chemistry industrial experienceExpert understanding of medicinal chemistry concepts along with strong working knowledge of protein-ligand interactions, conformational and structural analysis to enable creative solutions to drug discovery issues.Exceptional knowledge of ADME, physicochemical, biochemical and pharmacological principles as applied to drug discoveryExperienced in partnering closely with other functional areas including: computational chemistry, DMPK, in vivo pharmacology, CMC, etc.Significant operational experience in one of the following disciplines: Analytical Chemistry, Computer Aided Drug Design, Structural Biology, Formulation Sciences, in vitro and/or in vivo ADME



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