Immunology Research Associate I, II

1 month ago

Brisbane, California, United States GenEdit Full time

Immunology Research Associate I, II

GenEdit is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload design, formulation, and screening and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy.

Job Description

We are seeking a talented and motivated research associate to join our team and help drive the development of genetic medicines for immune-based diseases utilizing our hydrophilic nanoparticle (HNP) technology. This individual will be part of the Immune Program Team and will be responsible for executing studies as directed by the supervisor. She/he will be a key contributor to in vitro and ex vivo assay method development, HNP and payload screening, and ex vivo assays of tissue samples to identify lead therapeutic candidates that achieve desired immune modulating activity. The ideal individual will have a strong background in cellular immunology, immune response regulation, and immunological assays. Individuals with industry experience as a key individual contributor on project teams and a successful track record of teamwork are preferred. Position title will be commensurate with scope of responsibilities and years of relevant experience.

Education and Qualifications

· Bachelor or Master's degree in Immunology, Cell Biology, or related field

· Minimum of 2 years full-time research in industry or 3 years academic lab experience with a focus on immune assays

· Work authorization in the US is required

Required Skills

· Cell culture of primary immune cells (PBMC, APC, DC, T cells) and immune cell lines

● In vitro immune-based assays including but not limited to multicolor flow cytometry and analysis (FlowJo), cytokine analysis (MSD, Luminex), ELISA, ELISpot

● In vitro immune cell-based assays including but not limited to T cell:DC co-culture, cytotoxic T cell killing assay, MLR

● In Vitro screening, microplate cell-based assays, protein expression, viability, cytotoxicity, fluorescence, luminescence, automated microscopy and image analysis

● Experience with spleen, bone marrow and other immune tissue harvest and processing for ex vivo assays

● Experience with molecular biology is a plus (nucleic acid and protein extraction and purification, electrophoresis, PCR, RT-qPCR)

● Ability to execute on research protocols with accuracy and precision

● Excellent communication and organizational skills, ELN record keeping

At GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger. We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.

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