Computational Scientist, Protein Library Design

1 month ago


Boston, Massachusetts, United States Manifold Bio Full time

Manifold Bio is a biotech company pursuing a pipeline of protein therapeutics using novel molecular measurement technologies and library-guided protein engineering.Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process.We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics.Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.Manifold Bio is seeking an exceptional Computational Scientist to join our growing Compute team.You will work closely with experimental and hybrid scientists to design and analyze highly multiplexed protein library experiments.You will be expected to own and independently advance projects in areas related to your deep expertise such as protein design, DNA library design, or machine learning/biophysical modeling from MPRA data.You will work closely with our CSO and our other computational scientists to onboard new capabilities that advance the M-Design platform for data-driven engineering of drugs with desired properties.



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    Manifold Bio is a biotech company pursuing a pipeline of protein therapeutics using novel molecular measurement technologies and library-guided protein engineering. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding...


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