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Computational Scientist, Protein Library Design

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Boston, Massachusetts, United States Manifold Bio Full time

Manifold Bio is a biotech company pursuing a pipeline of protein therapeutics using novel molecular measurement technologies and library-guided protein engineering.Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process.We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics.Manifold Bio is seeking an exceptional Computational Scientist to join our growing Compute team.You will work closely with our CSO and our other computational scientists to onboard new capabilities that advance the M-Design platform for data-driven engineering of drugs with desired properties.PhD and/or 4+ years of equivalent experience in computational biology, bioinformatics, genomics, systems/synthetic biology, protein engineering, or a similar field working with biological sequences or systems; wet lab experience is a plusFirst-hand experience with any of the following: DNA/Protein sequence analysis, computational protein design, probabilistic modeling, machine learning, biophysical modeling, or antibody designExperience working with Next Generation Sequencing (NGS) data