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Research Investigator/Sr Research Investigator, Pharmacometrics
2 months ago
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: .
Summary/Scope
Responsible for the development and implementation of the model-informed drug development (MIDD) plan for drugs and other therapeutic agents in clinical development, in partnership with the CP&P Lead for the asset.
MIDD has emerged as a powerful complement to conventional drug development whereby pharmacometric (PMx: pharmacokinetic, exposure-response, and disease progression) models are developed with data from a variety of sources are utilized to inform drug development decisions and regulatory assessments. MIDD informs dose and regimen selection and hypotheses to be investigated in clinical studies; and supports regulatory assessments of the clinical pharmacology, and benefit-risk profile of a therapeutic agent by complementing data from clinical studies. Additionally, PMx analyses may also inform approval decisions, and in some cases be the primary basis for the approval.
Responsibilities will include, but are not limited to, the following: Partners with CP&P Lead to specify MIDD components of CP&P plan, with supervisionSupports CP&P Lead in planning, executing, and reporting of exploratory PMx analyses in support of drug development decisions, with supervisionResponsible for planning, executing, and reporting on formal PMx analyses included in CSRs, HA submissions, and responses to questions from HAs, with supervisionServes as MIDD SME, and supports CP&P lead in the development of therapeutic agents, with supervisionContributes to maintenance and refinement of PMx infrastructure, with supervisionContributes to CP&P initiatives Skills/Knowledge Required For Sr. Research Investigator we require Ph.D or PharmD. in relevant field with 2+ years experience hands on Pharmacometrics experience in industry, or hands on Post Doctoral Fellowship in Pharmacometrics activities may be considered. OR Masters Degree with 7 years Pharmacometrics experience required.For Research Investigator level we require PharmD in relevant field with 0-2 years Pharmacometrics experience in industry or hands on Ph.D Program OR Masters Degree with 5 years Pharmacometrics experience required.Basic quantitative data analysis, Data wrangling (merging and transforming data), visualization, basic PPK and E-R are all highly desiredProgramming experience is highly desired (e.g., R and NLME software such as NONMEM or Monolix)Knowledge of current practices and issues in Clinical Pharmacology and PharmacometricsStrong written and oral communication skills necessary to report on and deliver scientific presentationsDemonstrated ability to work in a dynamic team-oriented environment#LI-Hybrid
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through scienceTM , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit eeo -accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
