Senior Scientist II, Engineering
1 month ago
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description
Senior Scientist II, Engineering
The Process Research and Development organization within AbbVie invents synthetic processes to prepare active pharmaceutical ingredients (APIs) to enable the development of AbbVies pipeline, and ultimately to provide commercial manufacturing processes. AbbVie is seeking a highly motivated individual with a proven track record of accomplishment to join the API Pilot Plant Technical Operations (Tech Ops) group. This position will serve as a liaison between the Process Research and Development scientific functions and the API Pilot Plant organization. The successful candidate will assist in the optimization and scale-up of synthetic processes and facilitate the implementation of the processes and new technologies into the API Pilot Plant. The Scientist will also provide technical oversight during production campaigns and will support technical transfer to the ultimate commercial manufacturing site.
Responsibilities:
Management of processes entering the API Pilot Plant, including scheduling, equipment selection, materials tracking, authoring direction sets, obtaining safety analyses, and executing pre-runs.Participate in long range capital planning for Pilot Plant and expansion into new modalities (e.g. manufacturing of long acting injectable, lipid nanoparticles, oligonucleotides)Technical oversight of processes running in the API Pilot Plant, and responsibility for process-trouble shooting in collaboration with the project teams.Strong Technical Mentorship to TechOps group and project teams.Responsible for review and documentation of data for cGMP execution of chemical processes. Authors campaign summary reports.Identify, evaluate and implement new technologies for the pilot plant and/or identify opportunities to modify or leverage existing assets to enhance operational efficiency. Examples include automation, flow chemistry, novel separation, Process Analytical Technology (PAT) feedback control and drying technologies.Support the implementation of PAT. Assist with equipment specification, setup, data collection and analysis.Interface with project teams to ensure that processes are safe and operable.Partner with API development teams to optimize processes for scale-up. Identify appropriate equipment and configurations.Qualifications
Level and compensation will be commensurate with experience. BS, MS, or Ph.D in Chemical Engineering/Chemistry with 9+ (BS), 7+ (MS), or 2+ (Ph.D) years of experienceFamiliarity with modeling software such as MatLab, Python, C++, Ansys, COMSOLWorking Knowledge of analytical techniques such as HPLC, GC, NMR, and microscopyExperience with Process Analytical TechnologyPreferredExperience with laboratory experiments, process scale-up from lab to pilot plant and/or transferring a process from pilot plant to a commercial facility.Experience working in an API Plant environment. Familiarity with operation of chemical process equipment and systems.Experience in chemical processing unit operations including reactions, membrane separation, chromatography, tangential flow filtration.Understanding of cGMP, process safety requirements, and OSHA chemical hygiene plans.Key Leadership CompetenciesDemonstration of strong technical leadership and ability to mentor direct reportsBuilds strong relationships with peers and cross functionally with partners to enable higher performance.Learns fast, grasps the "essence" and can change course quickly where indicated.Raises the bar and is never satisfied with the status quo.Creates a learning environment, open to suggestions and experimentation for improvement.Embraces the ideas of others, nurtures innovation and manages innovation to reality.Strong interpersonal and communication skills with demonstrated ability to work within a team environment.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit
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