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Manufacturing Engineer
2 months ago
Biotech company in Redwood City, CA is currently looking for a Pilot Plant Associate for their Downstream team. Bellow the Activities this person will be in charge of:
Responsibilities:
- Perform pilot scale downstream purification process and manufacturing (post cell lysate to final formulation) by utilizing column chromatography, CsCl, UFDF, and various filtration steps.
- Follow good documentation practices to maintain accurate records.
- Work closely with team members to perform buffer preparation.
- Set-up, operate and maintain required downstream laboratory equipment.
- Maintain reagent, sample, and consumables inventory.
- Assist with data entry and data analysis in Excel and/or other statistical programs.
- Work closely with the downstream team to perform downstream experiments.
- Ensure safe workplace in compliance with the company and EHS' rules and regulations.
- Work with Assay Development and Quality Control to coordinate testing.
- Work to identify optimize, revise, and update current process batch records, protocols, and procedures to make them more robust and streamlined.
About you:
- Requires a Bachelor’s degree (or higher) in chemical/biochemical engineering or related fields with 4+ years of downstream purification experience.
- Proficient in general and non-routine laboratory skills including aseptic technique, multi-channel pipetting and biosafety cabinet operations.
- Hands on experience with buffer preparations, TFF (Hollow Fiber/Cassettes), UF/DF and Column Chromatography Purification. Experience working with AKTA Avant is required.
- Requires some knowledge of GxP standards, and the ability to apply compliance principles to laboratory practices.
- Able to work in a fast-paced environment as a team player with effective communication skills.
- Excellent computer skills; especially proficient in Excel and Word.
- Strong desire to learn new technologies, skill sets, and the science behind AAV processing.
- Strong teamwork and communication skills.
- Some overtime required, as needed.