Scientist NMR Spectroscopy Lead Discovery

2 months ago


South San Francisco, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Scientist NMR Spectroscopy - Lead Discovery & CharacterizationLive

What you will do

Lets do this. Lets change the world. In this vital role you will support drug discovery teams by providing NMR support for open access instrumentation, aiding in NMR experiment design, and providing expertise in structure elucidation studies by NMR techniques. In addition, you will participate in the buildout of the NMR facility and general maintenance / troubleshooting of NMR instruments.

The successful candidate will be expected to interact effectively in a cross functional setting, engaging with drug discovery scientists to determine how NMR studies might facilitate the progression of their programs. You will be part of multifunctional teams, working closely with medicinal chemists, purification scientists, biophysicists, mass spectrometrists and other subject matter experts. Responsibilities include:

  • provide high quality reports and presentations to internal drug discovery teams

  • identify and implement novel NMR-based technologies that will improve or accelerate the drug discovery process

  • liaison with the local scientific community to bring in new technologies to the department

  • Additional responsibilities may include mentoring junior-level staff, participating in national and international scientific meetings, and providing scientific reports that support the generation of publications, patents, or regulatory submissionsWin

    What we expect of you

    We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.Basic Qualifications:

  • Doctorate degree with relevant experience

    OR

  • Masters degree and 2 years of scientific experience

    OR

  • Bachelors degree and 4 years of scientific experience in the biopharmaceutical industry

    AND

  • In-depth understanding of NMR spectroscopy and structure elucidation of small molecules including quantitative methods (qNMR), dynamics and conformational changes.

Demonstrated ability to apply 1D (1H, 13C, 19F, 31P, 15N, etc.) and 2D (COSY, TOCSY, ROESY, HSQC, HMBC, etc.) NMR techniques including pulse sequence implementation or modification.

Experience in structure elucidation software (e.g. ACD, Bruker) for NMR.

Preferred Qualifications:

Ph.D. in chemistry or equivalent with at least 2 years of relevant experience in NMR spectroscopy preferable in the pharmaceutical industry.

Strong working knowledge of drug discovery and the development of therapeutics. Experience working in a cross functional, matrixed, and global research organization.

Understanding of compound purification and structure confirmation by LC-MS/MS utilized in modern drug-discovery.

Outstanding organizational, interpersonal and communication skills.

Established scientific reputation in the field of NMR Spectroscopy as evidenced by external publication and presentations.Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models, including remote work arrangements, where possibleApply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.comApplication deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.



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