Scientist, Antibody Discovery

2 weeks ago


South San Francisco, United States Planet Pharma Full time

Position Summary:


We are looking for a highly motivated Scientist Consultant with background in molecular biology and protein biochemistry to join our Antibody Discovery Group in South San Francisco. The Scientist Consultant will be responsible for supporting molecular biology efforts devoted to generating antibody/protein expression constructs and library generation. This individual will work closely with members of the Antibody Discovery Team to support Large Molecule therapeutic programs.


Responsibilities:


Design recombinant antibody expression constructs to produce monoclonal and bispecific antibodies in various molecular formats

Perform high-throughput molecular cloning to generate recombinant antibody and protein expression constructs, including high-throughput sequence analysis, and DNA purification

Support NGS-based antibody discovery and engineering campaigns by constructing phage display libraries and performing phage selection

Organize DNA and glycerol bacteria samples for distribution and proper storage

Perform high-throughput ELISA and FACS screens, as needed

Work collaboratively with Large Molecule functional teams to ensure materials are delivered on time

Demonstrate collection and thorough analysis of data, and update Electronic Notebook records

Basic Requirements:


BS in Biology, Biochemistry, Biomedical Engineering, Cancer Biology, Pharmacology, or related field with 0-2 years of experience working in an academic or industry laboratory setting.

Additional Preferences:


Experience in various molecular biology techniques, including molecular cloning, site-directed mutagenesis, DNA purification, and phage or yeast display library construction

Experience in using bioinformatics and molecular biology software to analyze DNA and protein sequences for sequencing confirmation, NGS, cluster analysis, and design of de-novo expression constructs

Highly motivated, fast learner with strong organization skills to effectively present data and summary of results, and ability to solve problems

Excellent written and verbal communication skills

Strong interpersonal skills

Additional Information:


Physical Demands/Travel:


The physical demands of this job are consistent with a lab environment.


The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.


Work Environment:


This position’s work environment is in a Laboratory.



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