Sr. Associate Scientist, ADC Biology

1 week ago

Bothell, United States Pfizer Full time

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Associate Scientist in the oncology research unit (ORU) organization, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to develop breakthrough therapies. You will be part of a team that is addressing the critical task to support research of Oncology programs entering the candidate stage and proceeding into the clinic.

You will contribute to the generation of data packages to support regulatory filings and studies designed to broaden our understanding of the target biology, the molecule's mechanism of action (MoA) and the tumor's mechanism of resistance. You will be an essential member of this team and execute key experiments to address the basic and translational biology of novel drug targets, their molecular pathways, and their connection to human disease.

With your deep knowledge in the discipline, and technical expertise, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

  • Contribute to team goals by influencing at the work group/project team level.

  • Apply technical skills, scientific and functional knowledge to projects/ assignments within own work group/ project team independently and proactively.

  • Perform laboratory experiments to help establish robust disease biology, cell-based compound screening assays across a broad array of target classes for the project teams.

  • Prepare and present experimental results to project teams.

  • Comply with all safety training and good laboratory practices.

Qualifications

Must-Have

  • Bachelor's degree in biology, biochemistry, or related field and 3+ years of relevant experience in the Academic/biotech/pharmaceutical industry.

  • Master's degree in biology, biochemistry, or related field and 0+ years of relevant experience in the Academic/biotech/pharmaceutical industry.

  • Solid understanding of concepts of molecular, cellular, and cancer biology.

  • Proficiency in mammalian cell culture including management of frozen stocks and culturing under selective pressure.

  • Experience in cellular assays including cell proliferation and cytotoxicity assays.

  • Experience in immune cell-based assays such as fluorescent microscopy, flow-cytometry, and ELISA.

  • Ability to troubleshoot, interpret, and summarize scientific data.

  • Ability to communicate effectively with colleagues at all levels. Excellent communication skills, both written and oral.

  • Must be goal-oriented with the ability to handle multiple tasks.

Nice-to-Have

  • Experience creating and characterizing genetically modified cell lines using viral vector-based or electroporation/transfection-based techniques.

  • Understanding of molecular biology assays including DNA cloning, PCR, qPCR, and Western blotting.

  • Experience with oncology drug development.

  • Experience with high throughput and automated lab equipment and assays.

PHYSICAL/MENTAL REQUIREMENTS

Lifting, sitting, standing, walking, bending, ability to perform laboratory work.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Must adhere to safe laboratory work practices.

Additional Information:

  • Work Location Assignment:On Premise

  • Last Day to Apply: October 4, 2024

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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