Principal Scientist
1 month ago
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160 countries.
Working at Abbott
At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. Youâll also have access to:
Career development with an international company where you can grow the career you dream of
Free medical coverage for employees* via the Health Investment Plan (HIP) PPO
An excellent retirement savings plan with high employer contribution
Tuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelorâs degree.
A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune.
A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists.
The Opportunity
This position works out of our San Diego, CA location in the Infectious Diseases Division.
We are seeking an experienced Principal Scientist to oversee and conduct cutting-edge research in enzymology, to identify, characterize, optimize and develop proteins used for nucleic acid amplification and sample preparation technologies. Your expertise will be crucial in advancing our understanding of enzymatic processes and developing innovative solutions. Youâll collaborate with cross-functional teams, establish protocols, and drive scientific excellence.Â
Responsibilities
Lead protein characterization, optimization and development efforts, from design of experiments through laboratory studies
Perform kinetic, thermodynamic and structure-function studies
Apply computational modeling to drive protein characterization and optimization efforts
Initiate and oversee proteomics efforts in-house and via collaboration
Provide cloning, protein expression, separation and purification expertise
Implement mutagenesis studies to help characterize and optimize proteins of interest
Drive the introduction of new, optimized and/or modified proteins to improve product performance
Design and implement procedures, processes and key performance indicators to monitor, characterize and QC proteins
Provide high level analysis of experimental results
Provide written reports and oral presentations to executives
Ability to work as part of a team with excellent communication skills
Excellent communication and collaboration skills
Required Qualifications
Bachelor's Degree. in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience in similar area.
Preferred Qualifications
Ph.D.in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience.
Minimum ten years of full-time laboratory experience in an industrial setting
Hands-on expertise using kinetic, thermodynamic and structure-function experimental approaches
Expertise with computational modeling of proteins and protein/nucleic acid interactions to drive characterization of protein functionality and to drive the incorporations of protein modifications to improve/alter function Â
Extensive experience characterizing DNA/RNA interacting/binding proteins
Expertise in optimizing protein expression and purification methods
Expertise in developing, optimizing and performing in vitro enzymatic assays
Experience with high-throughput genetic/molecular screening a plus
Inventive, with ability to implement ideas in the laboratory
Strong problem-solving skills and the ability to analyze complex enzymatic processes
Extensive hands-on experience driving the analytical, biological and functional characterization of proteins
Expertise in computational structure/function modeling of DNA/RNA binding proteins
Track record of modifying and optimizing protein function to improve key performance characteristics
Ability to work as part of a team with excellent communication skills
* Participants who complete a short wellness assessment qualify for FREE coverage in our HIP PPO medical plan. Free coverage applies in the next calendar year.
Learn more about our health and wellness benefits, which provide the security to help you and your family live full lives:Â www.abbottbenefits.com
Follow your career aspirations to Abbott for diverse opportunities with a company that can help you build your future and live your best life. Abbott is an Equal Opportunity Employer, committed to employee diversity.
Connect with us at www.abbott.com, on Facebook at www.facebook.com/Abbott and on Twitter @AbbottNews and @AbbottGlobal.
The base pay for this position is $109,300.00 â $218,500.00. In specific locations, the pay range may vary from the range posted.
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