Research Scientist, Cell Biology

4 days ago

Cambridge, Massachusetts, United States GC Therapeutics Full time
About GC Therapeutics

GC Therapeutics is a pioneering genome-wide cell landscape exploration company that leverages an integrated synthetic biology and AI-driven platform for cell programming. Our patent-pending and proprietary pluripotent stem cell differentiation technology platform, TFomeTM, was developed in collaboration with Professor George Church's lab, a renowned expert in synthetic biology. This innovative platform enables the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency, and speed.

Job Summary

We are seeking a highly skilled and detail-oriented individual to join our growing product optimization group as a research associate. Under the supervision of the team lead and scientists, this candidate will be responsible for the maintenance, differentiation, and functional analysis of pluripotent stem cell (PSC) lines and their derivatives to support the development of cell-based therapeutics.

Key Responsibilities
  • General Laboratory Roles:
    • Participate in the design, planning, and execution of experiments.
    • Make observations, analyze results, and maintain a detailed laboratory journal.
    • Summarize results and create presentations for internal group meetings.
    • Work with other members of the research team and within GCTx to accomplish company goals.
    • Follow all safe laboratory practices and company policies.
  • Experimental Techniques:
    • Culture PSC lines, including maintenance and analysis (e.g., cell culture, transfection, preparation of media, passaging, cryopreservation).
    • Perform cell type differentiation, characterization, and experimental endpoint analysis, including flow cytometry, ELISA, and microscopy.
  • Molecular Biology:
    • Utilize techniques such as PCR, molecular cloning, and plasmid isolation.
Requirements
  • Essential Qualifications:
    • Experience with mammalian cell culture and preferred experience with PSCs.
    • B.Sc. or M.Sc. degree in biology, cell biology, bioengineering, biochemistry, or related discipline. Preferred prior industry experience.
    • 2+ year track record of lab experience.
    • Proven experience in molecular biology laboratory techniques.
    • Strong project management and organizational skills and ability to prioritize and multitask.
    • Effective communication with excellent organization and interpersonal skills.
    • Ability to work in a laboratory environment approximately 75% of the time, including weekend hours.
  • Additional Preferred Qualifications:
    • Ability to conduct high-quality presentations at internal meetings.
    • Authorship on scientific reports and manuscripts.
    • Experience in gene expression analysis and next-generation sequencing.
    • Knowledge of R, Python, and FlowJo.

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