Research Scientist Full-time
23 hours ago
100% ONSITE
The Fountain Group is seeking a Preformulation Scientist to contribute to preformulation research in a small, fast-paced team. This position resides within the Formulations Sciences group of Pharmaceutical Sciences. The candidate will work full time onsite and contribute to the execution of laboratory activities related to the transition of small molecule compounds from Discovery into Development in support of pre-clinical and clinical programs.
Responsibilities:
Prepare buffers and common lab solutions. Execute analytical experiments with XRPD, DSC, TGA, DVS, SEM, optical microscopy, and UPLC/HPLC (Empower). Screen excipients/formulation vehicles for solubility and stability to optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies. Perform drug substance and formulation stability studies to ensure optimal formulation design. Coordinate vehicle/formulation preparations for in vivo studies. Execute dissolution studies (Distek and Pion DISS) to support formulation development and FIH development. Maintain an accurate, timely, and compliant laboratory notebook.
Qualifications:
BS (2+ years pharma) or MS (1+ years pharma). Pharmaceutical Laboratory Industry Experience. Pre-formulation or formulation of pharmaceuticals. HPLC and or UPLC experience (Empower preferred). Analytical characterization techniques (XRPD / TGA / DSC / DSV). Common excipients and volumetric glassware.
Preferred:
Dissolution studies (Distek and Pion preferred). Small molecules. Pre-clinical formulation. Drug formulation stability studies.
Compensation:
Up to $44.67 per hour depending on experience
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