Postdoctoral Research Scientist

5 days ago


Reston, Virginia, United States Tucker Parker Smith Group (TPS Group) Full time

Job Summary:

The Tucker Parker Smith Group (TPS Group) is seeking a highly skilled Postdoctoral Research Scientist to join our R&D team as a Bioconjugation Expert. In this role, you will be responsible for leading the synthesis, optimization, and delivery of bioconjugates, focusing on polymers, proteins/peptides, lipids, and oligonucleotides.

Key Responsibilities:

  • Develop and implement novel linker chemistries and bioconjugation methods for targeted drug delivery.
  • Utilize advanced purification techniques, including liquid chromatography (RP, IEX, SEC, HIC, affinity, FPLC) and membrane filtrations (TFF).
  • Apply biochemistry techniques and analytical methods such as SEC-MALs, LCMS, SPR/BLI, ELISA, SDS-PAGE, and enzyme activity assays.
  • Collaborate cross-functionally to transfer materials and support in vitro and in vivo experiments.

Requirements:

  • Ph.D. in Chemical Engineering, Chemical Biology, Chemistry, or related fields is required; as well as 2+ years of industry/post-doc experience relating to drug development.
  • Extensive experience with bioconjugation strategies for polymers, proteins/peptides, lipids, and oligonucleotides.
  • Strong foundation in macromolecular chemistry, bioconjugation, analytical chemistry and/or chemical biology is strongly desired.
  • A record of accomplishments/publications in relevant scientific discipline and some hands-on experience in oligonucleotide delivery is preferred but not required.
  • Proficiency in bioconjugate purification techniques, including liquid chromatography methods and membrane filtration.
  • Familiarity with biochemistry techniques and analytical methods (SEC-MALs, LCMS, SPR/BLI, ELISA, SDS-PAGE, enzyme assays).


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