Director of Computational Chemistry

1 day ago


San Diego, California, United States X4 Life Sciences Full time

About the Role:

X4 Life Sciences is seeking a visionary Director of Computational Chemistry to spearhead the development and application of cutting-edge computational methods in drug discovery. This leader will drive the creation of innovative software infrastructure and workflows that accelerate our discovery efforts.

Key Responsibilities:

  • Strategic Leadership: Oversee the development of computational strategies that align with our company's goals and objectives.
  • Algorithm Development: Implement and scale advanced physics-based methods and machine learning algorithms to optimize our drug discovery pipeline.
  • Collaboration: Foster strong relationships with multidisciplinary teams to understand computational challenges and implement tailored solutions.
  • Software Engineering Excellence: Ensure that all code developed is scalable, extensible, and portable, and that software engineering best practices are consistently applied.
  • Scientific Innovation: Stay at the forefront of scientific and computational trends, identifying new approaches that can be integrated into our platform to enhance our drug discovery capabilities.
  • High-Performance Computing: Oversee the management of high-performance computing clusters, ensuring efficient use of resources and implementation of parallel programming techniques.

Requirements:

  • Molecular Modeling Expertise: Extensive experience in molecular modeling and molecular dynamics techniques, with proficiency in tools such as AMBER or OpenMM.
  • Advanced Computational Knowledge: Strong foundation in scientific algorithm development using frameworks such as PyTorch, JAX, etc., with a focus on physics-based methods.
  • Software Development Experience: Proficient in Python and C/C++, with a deep understanding of scientific software engineering best practices.
  • Parallel Programming & HPC: Experience in parallel computing with MPI, OpenMP, OpenACC, CUDA C/C++/Fortran, and managing HPC clusters (both CPU and GPU-based).
  • Workflow Management: Familiarity with workflow frameworks like pySLURM or equivalent HPC job scheduling systems.
  • Containerization: Proficient in using and deploying containers in scientific computing environments.


  • San Diego, California, United States X4 Life Sciences Full time

    About the Role:X4 Life Sciences is seeking a visionary Director of Computational Chemistry to spearhead the development and application of cutting-edge algorithms and machine learning techniques in drug discovery. This leader will drive the creation of sophisticated software infrastructure to overcome critical bottlenecks in drug design.Key...


  • San Diego, California, United States Johnson & Johnson Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist, Computer-Aided Drug Design to join our team at Janssen Research & Development, LLC. As a key member of our In Silico Discovery group, you will be responsible for developing and implementing computational strategies to support innovative modality-agnostic drug discovery.Key ResponsibilitiesDesign...


  • San Diego, California, United States Johnson & Johnson Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist, Computer-Aided Drug Design to join our team at Janssen Research & Development, LLC. As a key member of our In Silico Discovery group, you will be responsible for developing and implementing computational strategies to support innovative modality-agnostic drug discovery.Key ResponsibilitiesDesign...


  • San Diego, California, United States Johnson & Johnson Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist, Computer-Aided Drug Design to join our team at Janssen Research & Development, LLC. As a key member of our In Silico Discovery group, you will be responsible for developing and implementing computational strategies to support innovative modality-agnostic drug discovery.Key ResponsibilitiesDesign...


  • San Francisco, California, United States Eli Lilly and Company Full time

    About Eli Lilly and CompanyWe are a global healthcare leader headquartered in Indianapolis, Indiana, dedicated to making life better for people around the world. Our employees work together to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through...


  • San Diego, California, United States Klein Hersh International Full time

    About the RoleWe are seeking a highly skilled and experienced Computational Chemist to join our team at Klein Hersh International. As a key member of our drug discovery team, you will play a critical role in the analysis of newly discovered functional sites in proteins and contribute to the development of small molecules targeting various classes of...


  • San Diego, California, United States University of California Full time

    Special InstructionsTo ensure thorough consideration, qualified applicants must submit a complete online application that includes the required items (additional materials will not be reviewed). References to resumes or other uploaded documents within the online application will be considered an "incomplete" application; please enter "N/A" if any section...

  • Lead Scientist

    3 weeks ago


    San Diego, California, United States Flexi Finance Full time

    Principal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewWorking with UsAt Flexi Finance, we redefine the conventional work experience. Here, you will engage in fascinating and impactful projects that contribute to the advancement of financial solutions. Collaborating with talented teams, you will have the opportunity...

  • Lead Scientist

    3 weeks ago


    San Diego, California, United States Flexi Finance Full time

    Principal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewAbout UsAt Flexi Finance, we are committed to delivering innovative solutions that have a meaningful impact on the financial industry. Our work environment is designed to foster creativity and collaboration, allowing our employees to thrive in their careers while...

  • Lead Scientist

    3 weeks ago


    San Diego, California, United States Flexi Finance Full time

    Principal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewAbout UsAt Flexi Finance, we are dedicated to making a significant impact in the financial sector through innovative solutions. Our work environment is characterized by a commitment to excellence, collaboration, and diversity. Here, you will find opportunities...

  • Lead Scientist

    3 weeks ago


    San Diego, California, United States Flexi Finance Full time

    Principal Scientist - Medicinal Chemist & AI/MLStatus: ArchivedCompany: Flexi FinanceJob OverviewAbout UsAt Flexi Finance, we are dedicated to transforming the financial landscape through innovative solutions. Our commitment to excellence drives us to seek talented individuals who are eager to contribute to meaningful projects that impact lives.Role...


  • San Francisco, California, United States Archdiocese of San Francisco Department of Catholic Schools Full time

    About the PositionThe Archdiocese of San Francisco Department of Catholic Schools is seeking a qualified Chemistry Teacher to join our team at Archbishop Riordan High School.Job SummaryWe are looking for a dedicated and experienced educator to teach Chemistry to students in grades 9-12. The successful candidate will have a strong background in Chemistry and...


  • San Francisco, California, United States Archdiocese of San Francisco Department of Catholic Schools Full time

    About the PositionThe Archdiocese of San Francisco Department of Catholic Schools is seeking a highly qualified Chemistry Teacher to join our team at Archbishop Riordan High School.Job SummaryWe are looking for a dedicated and passionate educator to teach Chemistry to students in grades 9-12. The successful candidate will have a strong background in...

  • Chemistry Instructor

    2 weeks ago


    San Francisco, California, United States Archdiocese of San Francisco Department of Catholic Schools Full time

    About the Position:The Archdiocese of San Francisco Department of Catholic Schools is seeking a qualified Chemistry Teacher to join our team at Archbishop Riordan High School. As a Chemistry Teacher, you will be responsible for teaching Chemistry to students in grades 9-12.Key Responsibilities:Design and implement a spiral curriculum with clear objectives...


  • San Diego, California, United States Clinical Dynamix Full time

    About the Role:Clinical Dynamix is seeking a highly motivated and talented peptide chemistry leader to join our new discovery peptide research group. As a Senior Research Scientist, Peptide Chemistry, you will work on the design, synthesis, and characterization of novel peptides and peptide conjugates to discover next-generation peptide-based...


  • San Francisco, California, United States Johnson Service Group Full time

    Job DescriptionJohnson Service Group is seeking a highly skilled Director, Peptide Chemistry R&D to lead our Peptide Research Department. As a key member of our team, you will be responsible for overseeing peptide design, synthesis, and research projects, collaborating with global teams and clients, and driving innovative solutions in peptide drug...


  • San Diego, California, United States Clinical Dynamix Full time

    Lead Scientist, Peptide Chemistry Innovations Clinical Dynamix is a pioneering biopharmaceutical organization dedicated to addressing significant health challenges through innovative solutions. Our mission is to develop transformative therapies for patients suffering from complex neurological, endocrine, and psychiatric conditions. With a diverse portfolio...


  • San Francisco, California, United States Johnson Service Group Full time

    Position Overview:Johnson Service Group is seeking a highly qualified individual for the role of Director of Peptide Chemistry R&D. This pivotal position is essential for leading the Peptide Research Department and managing various peptide-related projects. Key Responsibilities:As the Director, you will: Oversee the Peptide Research Department, ensuring...


  • San Francisco, California, United States Johnson Service Group Full time

    Position Overview:Johnson Service Group is seeking a highly qualified individual for the role of Director of Peptide Chemistry R&D. This pivotal position will be based in a dynamic environment focused on advancing peptide research. The Director will be responsible for steering the Peptide Research Department, managing peptide design, synthesis, and various...


  • San Francisco, California, United States University Of San Francisco Full time

    Position Overview:We are seeking a dedicated Chemistry Teaching Assistant to support our academic team at the University of San Francisco. This role involves a variety of responsibilities aimed at enhancing the educational experience for students in the Chemistry program.Key Responsibilities:Conduct laboratory sessions and provide hands-on instruction to...