Mass Spectrometry Research Scientist

2 weeks ago

Colorado Springs, Colorado, United States AOA Dx Full time

Join AOA Dx as a Mass Spectrometry Research Scientist. Our innovative tumor marker ganglioside platform, GlycoLocateTM, is leading advancements in early cancer detection.

We are looking for a skilled and knowledgeable Scientist with a background in chemistry, biochemistry, or a related discipline, particularly with hands-on experience in Mass Spectrometry and HPLC techniques. In this role, you will be tasked with conducting, troubleshooting, and independently designing high-throughput experiments utilizing our cutting-edge LC-MS/MS and HPLC instruments. A profound understanding of mass spectrometry, HPLC, and large-scale 'omics' analysis methods, along with practical experience in method development within a mass spectrometry-focused laboratory, is essential.

Key Responsibilities

  • Design and execute high-throughput experiments to analyze lipid content in serum using tandem MS platforms for biological characterization or analytical method development.
  • Analyze lipidomic data independently to derive insights related to cancer biology or analytical method optimization.
  • Develop methods for analyte separation, detection, and quantification using HPLC with ELSD.
  • Establish quarterly objectives, metrics, and milestones, tracking progress over time.
  • Collaborate with fellow scientists, research associates, and technicians to organize and allocate tasks weekly.
  • Present research findings and progress updates in team meetings to a diverse audience.
  • Operate, maintain, and optimize LC-MS instruments with precision.
  • Troubleshoot instrument malfunctions, calibrate equipment, and perform routine maintenance.
  • Maintain detailed records of experiments and results through an electronic lab notebook.
  • Contribute to the enhancement and optimization of analytical methodologies.
  • Stay informed about emerging trends and advancements in mass spectrometry technology.

Qualifications

  • PhD in Analytical Chemistry, Biochemistry, Biology, or a related field.
  • Consideration will be given to candidates with M.S. or B.S. degrees accompanied by relevant expertise and experience.
  • A minimum of 4+ years of practical experience in operating and maintaining HPLC/LC-MS systems.
  • Knowledge of biological sample preparation and extraction techniques for subsequent LC-MS and HPLC analysis.
  • Required industry experience in biotech or pharma is based on degree: 2+ years preferred for PhD holders, 3+ years for M.S. holders, and 5+ years for B.S. holders.
  • Proficiency in LC-MS and HPLC operation and troubleshooting is essential.
  • Strong analytical and problem-solving abilities.
  • Meticulous attention to detail and the capacity to maintain accurate records.
  • Effective communication skills and the ability to work collaboratively within a team.

The compensation range for this position is $105,000 to $125,000 annually, reflecting various geographic considerations. Actual salary and seniority level will be determined based on relevant experience and qualifications.

AOA Dx provides competitive benefits, including unlimited PTO, comprehensive health, dental, and vision insurance, fully sponsored life and disability benefits, monthly cell phone reimbursement, and a 401k plan with employer matching.

AOA Dx is an equal opportunity employer, welcoming candidates from diverse backgrounds to apply. We cultivate an environment where individuals can pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation or expression, age, disability, veteran status, or any other legally protected characteristics.

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