Biologics Discovery Sciences Team Lead
3 weeks ago
**About AbbVie**
AbbVie is a global biopharmaceutical company dedicated to discovering and delivering innovative medicines and solutions that solve serious health issues. We strive to make a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.
Our mission is to drive innovation, transform lives, serve our community, and embrace diversity and inclusion. We are committed to operating with integrity and employing qualified individuals without discrimination based on race, color, religion, national origin, age, sex, physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, or any other protected characteristic.
**Job Description and Responsibilities:**
As a Senior Scientist II in our Multispecifics Engineering team, you will be responsible for designing, engineering, and producing multispecific biologics to support AbbVie’s various therapeutic areas. You will evaluate and integrate state-of-the-art technology to improve therapeutic production platforms and provide leadership to your team members.
**Key Responsibilities include:
- Responsible for design, engineering and production of multispecific biologics to support all Abbvie therapeutic areas
- Evaluate and integrate state-of-the-art technology to improve therapeutic production platforms, and demonstrate creative “out-of-the-box” thinking to solve difficult problems
- Supervise 1-2 scientists, evaluate team performance, and is accountable for the effective performance of team
- Serve as a Multispecifics Engineering representative for cross-functional teams, and contribute scientific insights into multiple projects across various therapeutic areas; recognized expert in multispecifics design and production
- Serve as the Biologics lead on projects to coordinate activities and transitions from hit generation through candidate nomination
- Identify and solve technical problems independently, conceive and implement innovative process research ideas
- Ensure consistency and quality of technical reports
- Provide project update, analysis and advice to cross-functional teams and senior management
- Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
**Education and Qualifications:**
- PhD, MS, or BS degree in Biochemistry, Biochemical engineering or related disciplines with typically 4+ (PhD), 10+ (BS) or 12+ years of experience
- Extensive experience in multispecific biologics engineering and knowledge of biologic pipeline progression from exploratory through candidate nomination
- Extensive experience with protein, biologics, fragments, and multi-specifics design, expression and purification
- Experience managing direct reports and providing performance evaluations and development opportunities
- Program management experience preferred
- Experience with CRO coordination
- Ability to explore and develop new approaches to further advance innovative purification and screening technologies for multispecifics
- Sound scientific understanding of current state of protein expression/separation/analytical technologies
- Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF); experience with developability screening for multispecifics preferred
- Strong molecular biology skills (e.g. molecular cloning)
- Experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
- Excellent organizational skills and the ability to manage multiple projects simultaneously
- Team player with the ability to operate in a fast-paced multi-disciplinary environment
- Adapt to rapid changes in project priorities and timelines
- Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred
- Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude
**Benefits and Compensation:**
- Estimated salary range $140,000-$180,000 per year
- Comprehensive benefits package including paid time off, medical/dental/vision insurance, and 401(k) matching
- Eligible for short-term and long-term incentive programs
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