Multispecific Biologics Engineer

3 weeks ago

Worcester, Massachusetts, United States AbbVie Full time

**Job Overview**

AbbVie, a leading biopharmaceutical company, seeks an experienced Multispecific Biologics Engineer to join its Biologics Discovery Sciences group. The successful candidate will be responsible for designing, engineering, and producing multispecific biologics to support AbbVie's various therapeutic areas.

As a key member of the team, you will evaluate and integrate state-of-the-art technology to improve therapeutic production platforms. Your creative problem-solving skills and ability to think outside the box will be essential in driving innovation within the organization.

The ideal candidate will have extensive experience with biologics and multispecifics production platforms, analytical characterization (e.g., SEC, MS), and a proven track record of implementing multispecific engineering and production strategies. People and project management experience are also highly valued.

**Key Responsibilities:**

  • Responsible for design, engineering and production of multispecific biologics to support all Abbvie therapeutic areas
  • Evaluate and integrate state-of-the-art technology to improve therapeutic production platforms, and demonstrate creative “out-of-the-box” thinking to solve difficult problems
  • Supervise 1-2 scientists, evaluate team performance, and is accountable for the effective performance of team
  • Serve as a Multispecifics Engineering representative for cross-functional teams, and contribute scientific insights into multiple projects across various therapeutic areas; recognized expert in multispecifics design and production
  • Serve as the Biologics lead on projects to coordinate activities and transitions from hit generation through candidate nomination
  • Identify and solve technical problems independently, conceive and implement innovative process research ideas
  • Ensure consistency and quality of technical reports
  • Provide project update, analysis and advice to cross-functional teams and senior management
  • Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents

**Qualifications and Requirements:**

  • PhD, MS, or BS degree in Biochemistry, Biochemical engineering or related disciplines with typically 4+ (PhD), 10+ (BS) or 12+ years of experience
  • Extensive experience in multispecific biologics engineering and knowledge of biologic pipeline progression from exploratory through candidate nomination
  • Extensive experience with protein, biologics, fragments, and multi-specifics design, expression and purification
  • Experience managing direct reports and providing performance evaluations and development opportunities
  • Program management experience preferred
  • Experience with CRO coordination
  • Ability to explore and develop new approaches to further advance innovative purification and screening technologies for multispecifics
  • Sound scientific understanding of current state of protein expression/separation/analytical technologies
  • Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF); experience with developability screening for multispecifics preferred
  • Strong molecular biology skills (e.g. molecular cloning)
  • Experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
  • Excellent organizational skills and the ability to manage multiple projects simultaneously
  • Team player with the ability to operate in a fast-paced multi-disciplinary environment
  • Adapt to rapid changes in project priorities and timelines
  • Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred
  • Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude

**Additional Information:**

  • Estimated salary range $140,000-$180,000 per year depending on qualifications and experience
  • Comprehensive benefits package including paid time off, medical/dental/vision insurance, and 401(k) matching
  • Eligible for short-term and long-term incentive programs

  • Multispecifics Engineer

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    About the RoleWe are seeking an experienced Senior Scientist II to join our team in Multispecific Engineering. As a key member of our Biologics Discovery Sciences group, you will be responsible for designing, engineering, and producing multispecific biologics to support various therapeutic areas at AbbVie.ResponsibilitiesDesign and develop novel...

  • Engineer of Multispecific Protein Therapies

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    ResponsibilitiesDesign and engineer multispecific biologics to support early- and late-stage discovery programsEvaluate and integrate state-of-the-art technology to improve therapeutic production platformsServe as a Multispecifics Engineering representative for cross-functional teams and provide guidance as an expertIdentify and solve technical problems...

  • Senior Scientist II

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    **Job Summary**We are seeking a highly skilled and motivated Senior Scientist II to join our Multispecifics Engineering team at AbbVie. As a key member of the team, you will be responsible for designing, engineering, and producing multispecific biologics to support AbbVie’s various therapeutic areas.The ideal candidate will have a Ph.D. in Biochemistry or...

  • Senior Biologics Scientist

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    About UsAt AbbVie, we strive to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.The PositionWe are seeking an experienced Senior Scientist II to join our team in Multispecific Engineering. As a key member of our Biologics Discovery Sciences group, you will be...

  • Biologics Research Scientist

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Job DescriptionAs a Senior Scientist I, Multispecific Engineering, you will play a critical role in supporting Discovery Biotherapeutics at AbbVie. Your primary responsibilities will include designing, engineering, and producing multispecific biologics to support all AbbVie therapeutic areas.You will evaluate and integrate state-of-the-art technology to...

  • Multispecifics Biopharmaceutical Development Expert

    9 hours ago

    Worcester, Massachusetts, United States AbbVie Full time

    Job DescriptionResponsibilitiesDiscover and engineer biopharmaceutical products through the development of multispecifics technologiesAnalyze and document data related to protein purification, molecular cloning techniques, and sequence analysis toolsPresent research findings and results to colleagues and managementRequirementsBS or MS in biology or related...

  • Biologics Discovery Sciences Team Lead

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    **About AbbVie**AbbVie is a global biopharmaceutical company dedicated to discovering and delivering innovative medicines and solutions that solve serious health issues. We strive to make a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our...

  • Engineering Manager

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    About the OpportunityWe are seeking an experienced Senior Scientist II to join our team in Multispecific Engineering. As a key member of our Biologics Discovery Sciences group, you will be responsible for designing, engineering, and producing multispecific biologics to support various therapeutic areas at AbbVie.Job DescriptionJob Title: Senior Scientist II,...

  • Multispecific Biologics Engineer

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Company OverviewAbbVie is a leading biopharmaceutical company dedicated to discovering and delivering innovative medicines and solutions that address serious health issues. Our mission is to have a remarkable impact on people's lives across various therapeutic areas, including immunology, oncology, neuroscience, and eye care.

  • Biological Research Scientist

    3 weeks ago

    Worcester, Massachusetts, United States Collabera Full time

    Job DescriptionWe are seeking a highly motivated Biological Research Scientist to join our team in the development of new cell lines for biopharmaceutical applications. The ideal candidate will have a strong background in mammalian cell culture, genetic engineering, and flow cytometry.The selected candidate will work on multiple projects simultaneously,...

  • Downstream Expert in Biologics Manufacturing

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Downstream Expert in Biologics ManufacturingWe are seeking an experienced Downstream Expert in Biologics Manufacturing to join our team at AbbVie. As a key member of our Purification Process Development group, you will be responsible for developing and implementing purification processes for biologics candidates. Your expertise in downstream process...

  • Analytical Chemist

    4 weeks ago

    Worcester, Massachusetts, United States Collabera Full time

    Job SummaryCollabera, a leading provider of software engineering solutions, is seeking an experienced Analytical Chemist to join its team. The successful candidate will be responsible for the analytical characterization of biologics and biopharmaceutical products using advanced techniques such as mass spectrometry and chromatography.ResponsibilitiesDevelop...

  • Biologics Discovery Scientist

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Company OverviewAbbVie is a global leader in the development of innovative therapies that make a remarkable impact on people's lives. We strive to have a profound influence across several key therapeutic areas – immunology, oncology, neuroscience, and eye care.We are passionate about delivering groundbreaking solutions that solve serious health issues...

  • Biological Process Development Specialist

    2 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    About the JobWe are looking for a highly skilled Biological Process Development Specialist to join our team at AbbVie Bioresearch Center in Worcester, MA. As a member of our Cell Culture Process Development group, you will be responsible for developing and supporting cell culture manufacturing processes for early and late phase clinical programs.Key...

  • Process Development Engineer

    11 hours ago

    Worcester, Massachusetts, United States AbbVie Full time

    About Our TeamThe ABC Downstream Purification Process Development team specializes in biologics process development, including monoclonal antibodies (mAbs) and other complex modalities. The team consists of experts in downstream purification who leverage cutting-edge scientific principles to develop and scale robust processes from lab-scale to GMP...

  • Therapeutic Protein Engineer

    4 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Salary RangeThe estimated salary for this role is $150,000 - $220,000 per year, depending on experience and qualifications. This figure includes a comprehensive package of benefits, including paid time off, medical/dental/vision insurance, and 401(k) eligibility.Job Role and ResponsibilitiesThis Senior Scientist II position plays a pivotal role in advancing...

  • Senior Bioprocess Engineer

    4 weeks ago

    Worcester, Massachusetts, United States Collabera Full time

    About Our TeamWe are a dynamic team of scientists working together to develop new cell lines for biopharmaceutical applications. As a Biological Research Scientist, you will play a critical role in achieving our team's objectives by developing and characterizing CHO cell lines using established and novel techniques.Key Benefits:Competitive salary range:...

  • Industrial Process Optimization Engineer

    4 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Job Overview:A career-defining opportunity awaits for a seasoned Senior Process Engineer to join AbbVie's team. This pivotal role involves providing engineering support for Biologics manufacturing, ensuring seamless operations and driving innovation.About the Company:AbbVie is a leading biopharmaceutical company dedicated to transforming lives through...

  • Downstream Purification Engineer

    3 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    About the TeamWe are a team of highly skilled scientists and engineers working together to develop innovative purification processes for various biologics modalities. Our goal is to ensure seamless technology transfer to pilot labs and cGMP manufacturing facilities, while maintaining the highest level of quality and safety.Responsibilities:Process...

  • Senior Biotechnology Specialist

    4 weeks ago

    Worcester, Massachusetts, United States AbbVie Full time

    Therapeutic Area FocusAs a member of AbbVie's High Throughput Antibody Production team, you will play a crucial role in advancing our therapeutic pipeline across various therapeutic areas, including immunology, oncology, and neuroscience.Your expertise in biologics drug discovery and engineering will be instrumental in developing cutting-edge automated...