Senior Research Scientist
4 days ago
We are seeking a highly skilled Senior Research Scientist to join our team at Apellis Pharmaceuticals. The successful candidate will be responsible for developing and implementing translational endpoint strategies for CNS Neurology projects, working closely with cross-functional teams to identify novel fluid, digital, imaging, and/or technology-related endpoints for use in preclinical and early-stage clinical neurology programs.
Key Responsibilities- Develop and execute preclinical studies to validate potential translational endpoints.
- Design and implement biomarker strategies for neurologic diseases to allow for subject selection, recruitment, and early go/no go decision making.
- Act as a primary neurology endpoint strategy SME supporting fluid, digital, or other exploratory endpoint strategy for CNS neurology programs.
- Contribute to the design and execution of clinical studies in close collaboration with program teams and the Translational Clinical Development and Clinical Pharmacology functions.
- Facilitate cross-functional collaboration between the Research and Clinical Development functions to transition research stage assets to clinical development.
- Ensure awareness of trends and emerging technology in the field of neurology endpoints through external assessment.
- Contribute to drafting manuscripts, reports, and other publications and presentations.
- Provide support for advisory boards, consultant meetings, and investigator meetings, including preparation and/or delivery of presentations.
- Cultivate relationships with external partners, such as preclinical and clinical investigators, clinicians, and scientists, in support of endpoint innovation and/or business development.
- PhD, PharmD, or MD in a related life science discipline.
- 5+ years of relevant translational development neurology experience.
- 3+ years' experience in CNS disease-related fluid, digital, imaging, or novel endpoint development.
- Extensive knowledge and hands-on experience in liquid and tissue biomarker development and interpretation.
- Proven leadership experience in matrix organization with constructive influential skills and ability to drive functional excellence.
- Proven experience in strategic program management and external collaboration to develop novel biomarker endpoints.
- Adept at creating and writing business presentations, including storyboarding.
- Strong people skills and experience leading diverse and geographically dispersed associates.
- Proven success in developing positive relationships with subordinates, team members, and senior management.
- Excellent verbal and written communication skills.
- Experience in a start-up or small company environment preferred, including willingness to work independently without significant support.
- Independent individual with high integrity and courage.
- Be a champion of collaboration in high-performing teams.
- Highly motivated with the ability to be flexible in a fast-paced environment.
The position may include wet lab and/or vivarium work.
Travel RequirementsWilling to travel ~10% of the time to conferences and external collaboration sites.
Benefits and PerksApellis offers a great benefit package, including health insurance with full premium coverage, 401K with company match, paid time off (PTO), long-term disability insurance, life insurance, and more. Visit https://www.apellis.com/careers/ to learn more.
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