Postdoctoral Research Fellow in Ophthalmology

3 weeks ago


Watertown, Massachusetts, United States Apellis Pharmaceuticals Full time
Job Summary

We are seeking a highly motivated and experienced scientist to join our Translational Development group as a Postdoctoral Fellow in Ophthalmology. The successful candidate will play a crucial role in advancing our understanding of ocular diseases and developing therapeutic strategies for future clinical practice by targeting the complement cascade.

Key Responsibilities
  • Establish in vivo screening cascades for new ocular therapeutics, including designing models of ocular disease and characterizing disease models for changes in relevant biology.
  • Contribute to ongoing pharmacokinetic and pharmacodynamic research projects, gaining diverse experience and understanding of pharmaceutical drug development.
  • Develop nonclinical models in mice and rats to investigate disease biology, with a particular focus on mechanistic interrogation of the pharmacological effects of potential drug candidates.
Requirements
  • A PhD or master's degree with extensive experience in ophthalmology.
  • Experience with vivarium responsibilities, including non-clinical ocular imaging, animal handling, intravitreal injection, eye dissection, perfusion.
  • Basic wet lab skills, including molecular biology and biochemistry techniques such as DNA and RNA extraction, lysate preparation, qPCR, protein quantification, Western blot/WES/JESS, and ELISA.
What We Offer

Apellis Pharmaceuticals is a global biopharmaceutical company that combines courageous science and compassion to develop life-changing therapies for some of the most challenging diseases patients face. We offer a dynamic and collaborative work environment, opportunities for professional growth and development, and a competitive compensation package.

For more information, please visit http://apellis.com or follow us on Twitter and LinkedIn.



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