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Principal Scientist, Pharmacokinetics and Pharmacodynamics
2 months ago
Lycia Therapeutics, a pioneering biotechnology company, is seeking a highly skilled Principal Scientist to join its team. As a key member of our research and development team, you will play a crucial role in advancing our innovative therapeutic candidates.
Key Responsibilities- Perform pharmacokinetic data analysis, including non-compartmental and compartmental analyses, to derive relevant pharmacokinetic parameters.
- Present results to interdisciplinary teams, contributing to project decisions and fostering a collaborative and transparent environment.
- Drive the application of quantitative pharmacokinetic-pharmacodynamic (PK-PD) modeling to guide LYTAC dose selection, dose regimen optimization, and exposure-response relationships in non-clinical studies.
- Author regulatory submissions and serve as a pharmacokinetics/clinical pharmacology subject matter expert during interactions with regulatory agencies.
- Collaborate closely with research and development teams to define project objectives and design innovative and scientifically rigorous pharmacokinetic studies.
- Represent the clinical pharmacology function and provide subject matter expertise on cross-functional clinical study teams.
- PhD in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, or related field with at least 7-8 years of pharmacokinetics or PK/PD modeling experience within a pharmaceutical, biotechnology, or research setting.
- Proven track record of designing, executing, and analyzing pharmacokinetic studies, integrating pharmacology and pharmacokinetics data to generate quantitative models.
- Strong proficiency in pharmacokinetic software (e.g., WinNonlin, NONMEM) and relevant modeling tools.
- Ability to adhere to tight timelines across multiple research projects and adapt to changing priorities.
- Highly motivated and organized team player with excellent written and oral communication skills.
